N-Acetyltyramine

N-acetyltyramine is a member of the class of tyramines that is tyramine in which one of the hydrogens of the amino group is replaced by an acetyl group. It has a role as a marine metabolite, a bacterial metabolite, an Aspergillus metabolite, an animal metabolite and a quorum sensing inhibitor. It is a member of acetamides and a member of tyramines. It derives from a tyramine.

GK3-015 was prepared according to the following reaction scheme 12General procedure: To a solution of EXAMPLE 5 2-{4-[2-(4-Chlorobenzenesulphonylamino)-ethyl]-phenoxy}-2-methylpropionic acid A mixture of 44.8 g. (0.25 mol) GK3-015 was prepared according to the following reaction scheme 12GK3-015 was prepared according to the following reaction scheme 12The diacetyltyramine is now dissolved in 500 ml. methanol. 800 ml. (0.8 mol) 1 N aqueous potassium hydroxide solution are added dropwise thereto, the temperature thereby increasing to about 30 C., and then maintained for 2 hours at an internal temperature of 50 C. The reaction mixture is then cooled, rendered weakly acidic with concentrated hydrochloric acid and the methanol evaporated off in a vacuum. The product which crystallizes out is filtered off with suction, thoroughly washed with water and then dried. The yield of

N-[2-(4-Hydroxyphenyl)ethyl]acetamide maintains anti-tumor properties and is derived from a marine bacterium named Streptoverticillium. Cytotoxin.

Molecular Weight:179.22
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.094628657
Monoisotopic Mass:179.094628657
Topological Polar Surface Area:49.3
Heavy Atom Count:13
Complexity:162
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes