 Home > Encyclopedia > CYNARIN

CYNARIN

CYNARIN structure

CAS No:
1182-34-9
Formula:
C25H24O12
Chemical Name:
CYNARIN
Synonyms:
(1S,2S,3S,4R)-1,4-bis[(E)-3-(3,4-dihydroxyphenyl)-1-oxoprop-2-enoxy]-2,3-dihydroxy-1-cyclohexanecarboxylic acid;CYNARIN(ARTICHOKE);CYNARIN(ECHINACEA);CINARAN;CINARINE;2-allyl-1,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo]oxy]-3,5-dihydroxycyclohexanecarboxylic acid;Indena Cinaran;1,4-Bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-3,5-dihydroxycyclohexane-1-carboxylic acid
Categories:
Biochemical Engineering > Plant Extracts

Description

1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid from Xanthii fructus, inhibits LPS-stimulated TNF-α production[1].

1,4-Di-O-caffeoylquinic acid is a quinic acid.

CYNARIN Basic Attributes

Molecular Weight：

516.45

Exact Mass：

516.45

EC Number：

214-655-7

DSSTox ID：

DTXSID1033373

Color/Form：

White

HScode：

2932999099

Characteristics

PSA：

211.28000

XLogP3：

1.99

Density：

1.64

Melting Point：

225-227 ºC

Boiling Point：

843.4±65.0 °C(Predicted)

Flash Point：

278.1±27.8 °C

Refractive Index：

1.719

Vapor Pressure：

1.92E-28mmHg at 25°C

Toxicity：

mouse,LD50,intraperitoneal,1900mg/kg (1900mg/kg),Archives Internationales de Pharmacodynamie et de Therapie. Vol. 117, Pg. 63, 1958.

PKA：

2.74±0.50(Predicted)

Critical Temperature & Pressure：

2-8°C

Safety Information

Transport codes：

UN 3077

hazard class code：

R22;R43;R50/53

safety instructions：

S36/37-S60-S61

Marks：

Xn;N

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

1,4-di-O-caffeoylquinic acid

CYNARIN Use and Manufacturing

Artichoke (1,3-biscaffeoylquinic acid), also known as astilin, artichokeric acid. Exist in Asteraceae artichoke (Cynara scolymus L.), forest Senecio nemorensis (Senecio nemorensis L.) whole grass, can also be chemically synthesized. It has the effect of choleretic, liver protection and cholesterol lowering. Clinically used to treat various diseases caused by insufficient liver function. Can also be used as a choleretic drug.

1,4-O-Dicaffeoylquinic Acid (CAS# 1182-34-9) is a phenolic antioxidant extracted from Scabiosa arenaria.

Computed Properties

Molecular Weight:516.4
XLogP3:1.5
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:9
Exact Mass:516.12677620
Monoisotopic Mass:516.12677620
Topological Polar Surface Area:211
Heavy Atom Count:37
Complexity:873
Defined Atom Stereocenter Count:2
Defined Bond Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of CYNARIN

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Cynarin

CAS No.: 1182-34-9

Content: 99.00%

Inquiry
Naturalin Bio-Resources Co.,Ltd Contact Supplier

CN
2 YRS

Business licensed Certified factory

Manufactory Supplier of Ginseng Extract,Hericium Erinaceus Extract,Cranberry Extract,Rosemary Extract,Echinacea Extract,Fruits Powders,API Ingredients,Food Ingredients,Natural Color,Natural antioxidant,Plant Extracts,Milk Thistle Extract,Green Tea Extract,Diosmin,Rutin

Artichoke Extract Cynara Scolymus L 5% Cynarin CAS.1182-34-9

CAS No.: 1182-34-9

Content: 5%

Inquiry

Learn More Other Chemicals

Cynarin

30964-13-7
25-Deoxyecdysone

22005-50-1
compoundk

160729-91-9
7-[4-[4-(2-bromophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one Formula

203395-84-0
Moscatilin Formula

108853-14-1
beta-sitosterol sulfate Formula

24815-93-8
Cocoa butter Structure

8002-31-1
(2β,3β,5β,22S)-22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one Structure

26361-67-1
What is escin IIa

158732-55-9
What is Carvacryl acetate

6380-28-5

Hot Searches: chem supplier; dicalcium phosphate price; where to buy ammonium nitrate fertilizer; anhydrous sodium sulfate price; compounded retatrutide; dimethylformamide msds

Guide of CYNARIN

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

CYNARIN

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.