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Tiotropium bromide

Tiotropium bromide structure

CAS No:
136310-93-5
Formula:
C19H22NO4S2.Br
Chemical Name:
Tiotropium bromide
Synonyms:
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-,bromide (1:1),(1α,2β,4β,5α,7β)-;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-,bromide,(1α,2β,4β,5α,7β)-;3-Oxa-9-azatricyclo[3.3.1.02,4]nonane,3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane deriv.;Tiotropium bromide;BA 679BR;Spiriva;tiopropium;(1α,2β,4β,5α,7β)-7-[(Hydroxydi-2-thienylacetyl)oxy]-9,9-di-methyl-3-oxa-9-azoniatricyclo[3.3.1.0]nonane bromide
Categories:
Active Pharmaceutical Ingredients > Respiratory Drugs

Description

Tiotropium Bromide (BA679 BR) is a muscarinic acetylcholine receptor (mAChR) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel.

Tiotropium bromide Basic Attributes

Molecular Weight：

472.42

Exact Mass：

471.017365

EC Number：

1308068-626-2

HScode：

29309070

Characteristics

PSA：

116

XLogP3：

-0.69150

Appearance：

White Solid

Melting Point：

218-220 °C

Storage Conditions：

Refrigerator

Safety Information

wgk germany：

hazard class code：

R36:Irritating to the eyes.

safety instructions：

S23-S24/25

Marks：

Precautionary statement(s)：

P201, P202, P260, P261, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P308+P313, P312, P314, P321, P322, P330, P332+P313, P337+P313, P362, P363, P405, P501

Hazard Statements：

H302

Tiotropium bromide Use and Manufacturing

Anti - Asthmatic. Atropine derivatives. Bronchodilators. Muscarinic receptor antagonist.

Drug Function and Efficacy

Unspecified

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Tiotropium bromide spray
Specifications	Each press contains 2.5 micrograms of tiotropium bromide

Tiotropium bromide spray
Specifications	Each press contains 2.5 μg of tiotropium bromide

Tiotropium bromide spray
Specifications	Each press contains 2.5 micrograms of tiotropium bromide

See More Related Drugs

Registered Holders

TAPI NL B.V.

France
Active
INDUSTRIALE CHIMICA S.R.L.

Italy
Active
Sinochem Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders