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Butyl glycolate

Butyl glycolate structure

Butyl glycolate 

structure
  • CAS No:

    7397-62-8

  • Formula:

    C6H12O3

  • Chemical Name:

    Butyl glycolate

  • Synonyms:

    Acetic acid,2-hydroxy-,butyl ester;Glycolic acid,butyl ester;Acetic acid,hydroxy-,butyl ester;Butyl glycolate;Butoxycarbonylmethanol;Butyl hydroxyacetate;Polysolvan O;n-Butyl glycolate;Butyl 2-hydroxyacetate

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Colorless Transparent Liquid


Liquid

Butyl glycolate Basic Attributes

132.16

132.16

230-991-7

3H5QAS0HZX

DTXSID6044725

Characteristics

46.5

0.53

Liquid

1.0±0.1 g/cm3

-26ºC

87-88 °C @ Press: 20.5 Torr

71.7±6.9 °C

1.429

Safety Information

NA 1993 / PGIII

1

63-41

23-24/25

Xn

P280-P305 + P351 + P338

H318-H361

|Danger|H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]|P280, P305+P351+P338, and P310|Aggregated GHS information provided by 2704 companies from 8 notifications to the ECHA C&L Inventory.|Warning|H227: Combustible liquid [Warning Flammable liquids]|P201, P202, P210, P264, P280, P281, P305+P351+P338, P308+P313, P337+P313, P370+P378, P403+P235, P405, and P501

Butyl glycolate Use and Manufacturing

Methods of Manufacturing

To a thermometer, condenser, 1L four-neck flask trap successively added glycolic acid (70percent) 200 g580 g of n-butanol and acidic ion exchange resin pretreated 10 g (pH = 2.0), heated to 120 , Adjust the system vacuum, so that the system to maintain a certain amount of return.Use the water separator to separate the water produced by the reaction.After tracking the amount of water to the theoretical amount, stop the reaction, cool to room temperature, filter, with a small amount of n-butanol washing acid resin.The resulting filtrate was recovered by decompression of n-butanol, Distillation gave 224 g of n-butylhydroxyacetate, Purity 99.5percent, yield 92percent.

Uses

Paint additives and coating additives not described by other categories

Production

100,000 - 500,000 lb

Paint and coating manufacturing|Acetic acid, 2-hydroxy-, butyl ester: ACTIVE

Computed Properties

Molecular Weight:132.16
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:132.078644241
Monoisotopic Mass:132.078644241
Topological Polar Surface Area:46.5
Heavy Atom Count:9
Complexity:80.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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