C.I. Acid Red 14

502.43

501.988129

222-657-4

DR4641L47F

DTXSID3021225

REDDISH-BROWN CRYSTALS

176.11000

6.08380

Reddish-brown crystals or dark maroon powder. (NTP, 1992)

>300ºC

>225℃

Soluble in water

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

LD50 oral in rat: > 10gm/kg

Can be explosive as a dust in air at certain concentrations. Moderately soluble in water.

Azo, Diazo, Azido, Hydrazine, and Azide Compounds

Explosive

C.I. ACID RED 14 may form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides.

NONH for all modes of transport

2

36/37/38

26-37/39

QK1925000

Xi

P261-P305 + P351 + P338

H315-H319-H335

DHHS/NTP; Carcinogenesis Bioassay of C.I. Acid Red 14 in F344/N Rats and B6C3F1 Mice (Feed Study) Technical Report Series No. 220 (1982) NIH Publication No. 82-1776

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Not Classified

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

A carcinogenesis bioassay of textile grade C.I. Acid Red 14 (67%-71% purity) was conducted by feeding diets containing 6,000 or 12,500 ppm of this dye for 103-104 wk to groups of 50 male F344 rats, 12,500 or 25,000 ppm to groups of 50 female F344 rats, and 3,000 or 6,000 ppm to groups of 50 B6C3F1 mice of either sex. Groups of 90 untreated rats of either sex and 50 untreated mice of either sex served as controls. ... Under the conditions of this bioassay, C.I. Acid Red 14 was not carcinogenic for F344 rats or B6C3F1 mice of either sex. Synonym: 4-hydroxy-3-(4-Sulfo-1-naphthalenyl)azo-1-naphthalenesulfonic acid, disodium. Levels of Evidence of Carcinogenicity: Male Rats: Negative; Female Rats: Negative; Male Mice: Negative; Female Mice: Negative.

FOLLOWING IV ADMIN OF 1 MG...TO RATS, 30-40% OF COLOR WAS EXCRETED UNCHANGED IN BILE. IT IS REDUCED BY LACTIC ACID BACTERIA.|BILIARY EXCRETION RATE OF AZO RUBINE S ADMIN IV TO RATS WITH LIGATED RENAL PEDICLES, REACHED APPARENT MAX WHICH WAS DEPRESSED BY PHENOLPHTHALEIN GLUCURONIDE OR PROBENECID. BILIARY EXCRETION OF THE DYE MAY INVOLVE AN ACTIVE TRANSPORT PROCESS.

ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits very toxic fumes of sulfur oxides, nitrogen oxides and Na2O. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

acid red 2C

ESSENTIALLY 100% AS A DYE

1-Naphthalenesulfonic acid, 4-hydroxy-3-[2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:2): ACTIVE|SPECIFICATIONS...BY BRITISH STANDARDS INSTITUTION (1960)...PRODUCT MUST CONTAIN MIN OF 85% CARMOISINE. FAO/WHO (1966)...ALSO...MIN OF 85% PURE COLOR. ...WHEN...NOT USED IN FOODS, DRUGS OR COSMETICS, ITS MFR & TESTING DO NOT CONFORM TO RIGID CHEM SPECIFICATIONS & ITS COMPOSITION MAY VARY...|...DYING WOOL, LEATHER & TO STAIN WOOD. IN US...USED TO COLOR COSMETICS UNTIL...1966, WHEN...REMOVED FROM APPROVED LIST FOR THIS USAGE (US CODE OF FEDERAL REGULATIONS, 1974). ... APPROVAL FOR ITS USE IN FOOD WAS WITHDRAWN IN JAPAN PRIOR TO 1966...FINLAND, NORWAY & SWEDEN...NO LONGER PERMIT USE...IN FOODSTUFFS.

MIXTURES OF THE ANTISEPTIC CHLORHEXIDINE ACETATE WITH DYES TARTRAZINE, CARMOISINE, OR METHYLENE BLUE WERE ANALYZED BY HIGH-PRESSURE LIQ CHROMATOGRAPHY.

EPA Safer Chemical Functional Use Classes -> Colorants|Safer Chemical Classes -> Yellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues|Food additives|Cosmetics -> Cosmetic colorant; Hair dyeing

Food Additives -> COLOUR;