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Almitrine bismesylate

Almitrine bismesylate structure

CAS No:
29608-49-9
Formula:
C26H29F2N7.2CH4O3S
Chemical Name:
Almitrine bismesylate
Synonyms:
1,3,5-Triazine-2,4-diamine,6-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-N2,N4-di-2-propen-1-yl-,methanesulfonate (1:2);s-Triazine,2,4-bis(allylamino)-6-[4-[bis(p-fluorophenyl)methyl]-1-piperazinyl]-,dimethanesulfonate;1,3,5-Triazine-2,4-diamine,6-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-N,N′-di-2-propenyl-,dimethanesulfonate;1-(4,6-Bis(allylamino)-2-s-triazinyl)-4-(4,4′-difluorobenzhydryl)piperazine bis(methane sulfonate);1-[4,6-Bis(allylamino)-s-triazin-2-yl]-4-(di-p-fluorobenzhydryl)piperazine bis(methanesulfonate);1-(4,6-Diallylamino-2-triazinyl)-4-(di-p-fluorobenzhydryl)piperazine bis(methanesulfonate);Almitrine bismethanesulfonate;Almitrine dimesylate;Vectarion;Almitrine bismesylate;Almitrine dimethanesulfonate;Almitrine mesylate
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Almitrine mesylate, a peripheral chemoreceptor agonist, inhibits selectively the Ca2+-dependent K+ channel.

Molecular Weight：

669.76

Exact Mass：

669.221497

EC Number：

249-726-1

PSA：

195

XLogP3：

5.57570

Appearance：

COA

Melting Point：

243 °C (decomp)

Boiling Point：

606.2°C at 760 mmHg

Vapor Pressure：

1.21E-14mmHg at 25°C

Toxicity：

Oral-Mouse LD50: 2000 mg/kg; Abdominal cavity-mouse LD50: 370 mg/kg

Flammability characteristics：

Combustible; burning produces toxic nitrogen oxides, sulfur oxides and fluoride fumes

Storage features：

Treasury is ventilated, low temperature and dry; stored separately from food materials

Toxicity class：

highly toxic

Respiratory stimulant.

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