 Home > Encyclopedia > 3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

3-cyclopropyl-1-(2-fluoro-4-iodophenyl... structure

CAS No:
871700-24-2
Formula:
C18H15FIN3O4
Chemical Name:
3-cyclopropyl-1-(2-fluoro-4-iodophenyl...
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Request for Quotation

3-cyclopropyl-1-(2-fluoro-4-iodophenyl... Basic Attributes

Molecular Weight：

483.2322732

Exact Mass：

483.009

Characteristics

PSA：

81.2

XLogP3：

2.4

Density：

1.94±0.1 g/cm3(Predicted)

Boiling Point：

518.2±60.0°C at 760 mmHg

3-cyclopropyl-1-(2-fluoro-4-iodophenyl... Use and Manufacturing

To a 2: 1 mixture (34.6 g) of 3-cyclopropyl-l-(2-fluoro-4- iodophenyl)-6-methylamino-lH-pyrimidine-2, 4-dione 52 and 1- cyclopropyl-3-(2-fluoro-4-iodo-phenyl)6-methylamino-1H- pyrimidine-2, 4, -dione 53 obtained in Step 4, and 2-methylmalonic acid 54 (10.2 g) was added acetic anhydride (173 ml), and the mixture was stirred at 100°C for 2 hrs. After allowing to cool to room temperature, the reaction mixture was concentrated under reduced pressure. Acetone (104 ml) was added to the residue, and the mixture was stirred with heating under reflux for 30 min. After allowing to cool to room temperature, the precipitated crystals were collected by filtration and dried to give 3- cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6, 8-dimethyl- lH, 8H-pyrido[2, 3-d]pyrimidine-2, 4, 7-trione 55 (15.1 g, yield from 48, 21percent) as colorless crystals.

Computed Properties

Molecular Weight:483.2
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:483.00913
Monoisotopic Mass:483.00913
Topological Polar Surface Area:81.2
Heavy Atom Count:27
Complexity:806
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

hubei bocare chemical Co.ltd Contact Supplier

CN
1 YR

Business licensed

Trader Supplier of pregabalin,Tirzepatide,Retatrutide,Food Additives,semaglutide,Cosmetics material,Food additive,Chemical intermediate,Active pharmaceutical ingredients

3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

CAS No.: 871700-24-2

Grade: Pharmaceutical Grade

Content: 99.9%

Inquiry
Jinshu Peptide Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Distributor Supplier of peptone

High quality factory sale best service 3-cyclopropyl 1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

CAS No.: 871700-24-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry

Latest News on 3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

Learn More Other Chemicals

(3S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid

103733-66-0
2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

1083168-84-6
2-iodo-2,3-dihydroinden-1-one

113021-30-0
2,2-DIMETHYL-N-[3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDIN-2-YL]-PROPIONAMIDE Formula

532391-30-3
6-Methylbenzoxazole Formula

10531-80-3
Methyl N-formylanthranilate Formula

41270-80-8
1-(4-amino-3,5-dichlorophenyl)-2-(dimethylamino)ethanol Structure

4812-69-5
2,5-Dihydroxy-N-(2-hydroxyethyl)benzamide Structure

61969-53-7
What is Benzenemethanol, α-(aminomethyl)-4-(1-methylethyl)-

91339-24-1
What is 5-Hydroxy-2-iodobenzaldehyde

50765-11-2

Hot Searches: triethylamine; cadmium sulfide; ambroxol ambroxol; aluminum phosphate formula; 1 3 bisphosphoglycerate; propenoic acid

Guide of 3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

Basic Attributes
Characteristics
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
Learn More Other Chemicals

3-cyclopropyl-1-(2-fluoro-4-iodophenyl...

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.