2-Methylnaphth[2,1-d]oxazole

clear yellow-brown to orange-brown liquid

Surfactant mediated solvent-free protocols were also successfully extended to the conversion of aryl nitro compounds to aryl acetamides. Thus, solvent-free acetamidation reactions involved treating a mixture of the aryl nitro compound (1 eq) with potassium thioacetate (4 eq.) in presence of dry Triton-X 405 (cat) at about 130 DEG C for about 3 hours producing the corresponding arylacetamide in greater than about 95percent conversion (HPLC and GC) and selectivity. Representative results for acetamidation of aryl nitro compounds are summarized in Table 2. The general reaction for the acetamidation of the aryl nitro compound is as follows:

Molecular Weight:183.21
XLogP3:3.4
Hydrogen Bond Acceptor Count:2
Exact Mass:183.068413911
Monoisotopic Mass:183.068413911
Topological Polar Surface Area:26
Heavy Atom Count:14
Complexity:218
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes