gamma-Benzyl L-glutamate
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gamma-Benzyl L-glutamate
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CAS No:
1676-73-9
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Formula:
C12H15NO4
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Chemical Name:
gamma-Benzyl L-glutamate
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Synonyms:
L-Glutamic acid ÿ-benzyl ester;GLUTAMIC ACID(OBZL)-OH;GLUTAMIC ACID-GAMMA-BENZYL ESTER;H-L-GLU(OBZL)-OH;H-L-GLU(BZL)-OH;GAMMA-BENZYL-L-GLUTAMATE;GAMA-BENZYL L-GLUTAMATE;H-Glu(obzl)-oh ,98%
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CAS No:
Description
white powder
Recrystallise the ester from H2O and store it at 0o. [Estrin Biochemical Preparations 13 25 1971, Beilstein 6 IV 2538.]
gamma-Benzyl L-glutamate Basic Attributes
237.25
237.25
1885646
216-826-1
TSCA listed
White
29224999
Characteristics
89.6
-1.7
White Powder
1.2026 (rough estimate)
181-182 °C(lit.)
379.78°C (rough estimate)
211.5±28.7 °C
1.5200 (estimate)
2-8°C
9.12E-09mmHg at 25°C
27.2 º (c=2, 1N HCL)
2.20±0.10(Predicted)
2-8°C
Safety Information
IRRITANT
NONH for all modes of transport
3
22-24/25
Stable under normal temperatures and pressures.
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 6 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)
PBLG polymer
gamma-Benzyl L-glutamate Use and Manufacturing
Used in biochemical reagents and pharmaceutical intermediates.
L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).
L-Glutamic acid, 5-(phenylmethyl) ester: ACTIVE
Computed Properties
Molecular Weight:237.25
XLogP3:-1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:237.10010796
Monoisotopic Mass:237.10010796
Topological Polar Surface Area:89.6
Heavy Atom Count:17
Complexity:261
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of gamma-Benzyl L-glutamate
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