Carvedilol phosphate
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Carvedilol phosphate
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CAS No:
610309-89-2
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Formula:
C24H26N2O4.H3O4P.1/2H2O
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Chemical Name:
Carvedilol phosphate
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Synonyms:
2-Propanol,1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-,phosphate,hydrate (2:2:1);2-Propanol,1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-,phosphate (salt),hydrate (2:2:1);Carvedilol phosphate;SKF 105517D;Carvedilol phosphate hemihydrate;Carvedilol dihydrogen phosphate hemihydrate;Coreg CR
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CAS No:
Description
Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.IC50 Value: 3.8 μM ( inhibition of LDL oxidation)Target: beta Adrenergic ReceptorCarvedilol is a nonselective-blocking agent and is used in the treatment of hypertension and angina pectoris. As a third-generation β-adrenergic blocker (β-blocker), Carvedilol is able to reverse cardiac structural remodeling. Recentresults demonstrated that the effect caused by Carvedilol on car
Safety Information
|Warning|H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P273, P280, P302+P352, P321, P333+P313, P363, P391, and P501|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Carvedilol phosphate Use and Manufacturing
Treatment of congestive heart failure, left ventricular dysfunction following myocardial infarction, and management of hypertension.
Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients
Computed Properties
Molecular Weight:1027.0
Hydrogen Bond Donor Count:13
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:20
Exact Mass:1026.34287045
Monoisotopic Mass:1026.34287045
Topological Polar Surface Area:308
Heavy Atom Count:71
Complexity:557
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:5
Compound Is Canonicalized:Yes
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