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Home > Encyclopedia > Factory 3',5'-Difluoroacetophenone CAS...

Factory 3',5'-Difluoroacetophenone CAS...

Factory 3',5'-Difluoroacetophenone CAS... structure

Factory 3',5'-Difluoroacetophenone CAS... 

structure

Factory 3',5'-Difluoroacetophenone CAS... Basic Attributes

156.13

156.038666

DTXSID90333793

2914700090

Characteristics

17.1

1.8

colorless transparent liquid or white solid

1.2±0.1 g/cm3

34-38 °C(lit.)

190.7°C at 760 mmHg

70.3±15.9 °C

1.473

0.533mmHg at 25°C

Safety Information

NONH for all modes of transport

3

R36/37/38

S26-S36

Xi:Irritant

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Factory 3',5'-Difluoroacetophenone CAS... Use and Manufacturing

Dess-Martin periodinane (9.66 g, 22.8 mmol) was added portionwise to a solution of 1-(3, 5-difluorophenyl)ethanol (3.00 g, 19.0 mmol) in DCM (40 mL) cooled in an ice bath. The mixture was stirred at room temperature for 2 h, then concentrated under reduced pressure. The residue was purified by purified by column chromatography on silica gel using CombiFlash® apparatus eluting with EtOAc/hexanes (0-40percent). The purification gave 2.06 g (69.6percent) of the sub-title compound as a colorless oil.

Computed Properties

Molecular Weight:156.13
XLogP3:1.8
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:156.03867113
Monoisotopic Mass:156.03867113
Topological Polar Surface Area:17.1
Heavy Atom Count:11
Complexity:148
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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