Factory 3',5'-Difluoroacetophenone CAS...
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Factory 3',5'-Difluoroacetophenone CAS...
structure -
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CAS No:
123577-99-1
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Formula:
C8H6F2O
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Chemical Name:
Factory 3',5'-Difluoroacetophenone CAS...
- Categories:
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CAS No:
Factory 3',5'-Difluoroacetophenone CAS... Basic Attributes
156.13
156.038666
DTXSID90333793
2914700090
Characteristics
17.1
1.8
colorless transparent liquid or white solid
1.2±0.1 g/cm3
34-38 °C(lit.)
190.7°C at 760 mmHg
70.3±15.9 °C
1.473
0.533mmHg at 25°C
Safety Information
NONH for all modes of transport
3
R36/37/38
S26-S36
Xi:Irritant
P261-P305 + P351 + P338
H315-H319-H335
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 46 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Factory 3',5'-Difluoroacetophenone CAS... Use and Manufacturing
Dess-Martin periodinane (9.66 g, 22.8 mmol) was added portionwise to a solution of 1-(3, 5-difluorophenyl)ethanol (3.00 g, 19.0 mmol) in DCM (40 mL) cooled in an ice bath. The mixture was stirred at room temperature for 2 h, then concentrated under reduced pressure. The residue was purified by purified by column chromatography on silica gel using CombiFlash® apparatus eluting with EtOAc/hexanes (0-40percent). The purification gave 2.06 g (69.6percent) of the sub-title compound as a colorless oil.
Computed Properties
Molecular Weight:156.13
XLogP3:1.8
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:156.03867113
Monoisotopic Mass:156.03867113
Topological Polar Surface Area:17.1
Heavy Atom Count:11
Complexity:148
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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Factory 3',5'-Difluoroacetophenone CAS...
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