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Rosiglitazone

Rosiglitazone structure

CAS No:
122320-73-4
Formula:
C18H19N3O3S
Chemical Name:
Rosiglitazone
Synonyms:
2,4-Thiazolidinedione,5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-;5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione;BRL 49653;Rosiglitazone;5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione;Rosiglizole;5-[[4-[2-[N-Methyl-N-(2-pyridyl)amino]ethoxy]phenyl]methyl]thiazolidine-2,4-dione;TDZ 01;Rezult;Rosvel;Venvia;Nyracta
Categories:
Active Pharmaceutical Ingredients > Hormones and the Endocrine System

Description

Rosiglitazone is a type of thiazolidinedione antidiabetics. Thiazolidinedione are agonists for peroxisome-proliferator–activated receptor γ (PPAR-γ). PPAR-γ receptors are ligand-activated nuclear transcription factors that modulate gene expression, lowering blood glucose primarily by increasing insulin sensitivity in peripheral tissues. Rosiglitazone is widely used to lower blood glucose levels in patients with type 2 diabetes mellitus.

Rosiglitazone Basic Attributes

Molecular Weight：

357.43

Exact Mass：

357.43

EC Number：

1308068-626-2

HScode：

2934100000

Characteristics

PSA：

96.8

XLogP3：

3.1

Appearance：

Solid

Density：

1.315±0.06 g/cm3(Predicted)

Melting Point：

151-153 °C

Boiling Point：

585.0±35.0 °C(Predicted)

Flash Point：

307.6±25.9 °C

Refractive Index：

1.642

Water Solubility：

DMSO: ≥10mg/mL

Storage Conditions：

2-8°C

Vapor Pressure：

2.95X10-14 mm Hg at 25 deg C (est)

Safety Information

Packing level：

Hazard category：

6.1

Transport codes：

3280

wgk germany：

hazard class code：

36/38

safety instructions：

26-37/39

RTECS Number：

XJ5813850

Marks：

Stability/Shelf Life：

Stable under recommended storage conditions.

Precautionary statement(s)：

P201, P202, P264, P273, P280, P281, P305+P351+P338, P308+P313, P337+P313, P391, P405, P501

Hazard Statements：

H319

Rosiglitazone Use and Manufacturing

A potent and selective PPARγ agonist.

Computed Properties

Molecular Weight:357.4
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:357.11471265
Monoisotopic Mass:357.11471265
Topological Polar Surface Area:96.8
Heavy Atom Count:25
Complexity:469
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Rosiglitazone

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Rosiglitazone Raw powder CAS 122320-73-4 Rosiglitazone

CAS No.: 122320-73-4

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Hangzhou Hyper Chemicals Limited Contact Supplier

CN
YRS

Business licensed

Trader Supplier of Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

High Purity Rosiglitazone CAS 122320-73-4 Raw Powder Competitive Price Ready to Ship

Unit Price: nullnull /null null

CAS No.: 122320-73-4

Grade: Pharmaceutical Grade

Content: 98%

Inquiry

Learn More Other Chemicals

N-Desmethyl Rosiglitazone

257892-31-2
Rosiglitazone hydrochloride

302543-62-0
5-Hydroxy Rosiglitazone

257883-22-0
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86728-85-0
Liraglutide Formula

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183133-96-2
(7α)-3-Hydroxy-7-methylestra-1,3,5(10)-trien-17-one Structure

10448-96-1
Quingestanol Structure

10592-65-1
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11000-17-2
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11070-73-8

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Guide of Rosiglitazone

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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Rosiglitazone

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