L-Histidine hydrochloride monohydrate
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L-Histidine hydrochloride monohydrate
structure -
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CAS No:
5934-29-2
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Formula:
C6H9N3O2.ClH.H2O
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Chemical Name:
L-Histidine hydrochloride monohydrate
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Synonyms:
L-Histidine,hydrochloride,hydrate (1:1:1);Histidine,monohydrochloride,monohydrate,L-;L-Histidine,monohydrochloride,monohydrate;L-Histidine hydrochloride monohydrate;L-Histidine monohydrate monohydrochloride;35343-95-4
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CAS No:
L-Histidine hydrochloride monohydrate Basic Attributes
209.63
209.056717
4168261
211-438-9
X573657P6P
DTXSID00208089
29332990
Characteristics
93
0.80210
White Solid
1.485 g/cm3
251-252 °C (decomp) @ Solvent: Hydrochloric acid, 0.2N
458.9ºC at 760 mmHg
231.3ºC
H2O: 169.9 g/L (20 ºC)
Store at RT.
<1 hPa (20 °C)
9.9 º (c=11, 6 N HCl)
128.6 Ų [M-H]-
Safety Information
NONH for all modes of transport
3
22-36/37/38
22-24/25-36/37-26
MS3119000
Xn
Stable under normal temperatures and pressures.
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362
H315
|Warning|H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 7 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
L-Histidine hydrochloride monohydrate Use and Manufacturing
A by-product of lysine separation from defatted soybean hydrolysate. It is the weakest among basic amino acids and can be separated from other basic amino acids by passing through an ion exchange resin column. Or it can be separated into insoluble mercury salt, 3, 5-dichlorobenzene sulfonate, etc. It is obtained by hydrolysis of hemoglobin with hydrochloric acid. Manufactured by fermentation method.
The precursor of histamine depends on the catalysis of histidine decarboxylase
Computed Properties
Molecular Weight:209.63
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:209.0567189
Monoisotopic Mass:209.0567189
Topological Polar Surface Area:93
Heavy Atom Count:13
Complexity:151
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Drug Function and Efficacy
The ratio of essential amino acids to non-essential amino acids in this product is 1.04:1. Each amino acid can be effectively used in the synthesis of human protein and has high bioavailability.
Registered Holders
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PFANSTIEHL INC
Active
United States
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Shanghai Primano Amino Acid Co., Ltd.
Active
China
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Jinyao Pharmaceutical Co., Ltd.
Active
China
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L-Histidine hydrochloride monohydrate
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