2-Chlorobenzylidenemalononitrile Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | [(2-chlorophenyl)methylene]malononitrile |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | [(2-Chlorophenyl)methylene]malononitrile; 2-(2-chlorophenylmethylene)malononitrile; CS (lacrimator) |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Industrial and scientific research uses. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin irritation, Category 2
Skin sensitization, Category 1
Acute toxicity - Category 1, Inhalation
Specific target organ toxicity â single exposure, Category 3
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H301 Toxic if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H330 Fatal if inhaled H335 May cause respiratory irritation H400 Very toxic to aquatic life |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P273 Avoid release to the environment. |
| Response | P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P320 Specific treatment is urgent (see ... on this label). P319 Get medical help if you feel unwell. P391 Collect spillage. |
| Storage | P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| [(2-chlorophenyl)methylene]malononitrile | [(2-chlorophenyl)methylene]malononitrile | 2698-41-1 | 220-278-9 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Pain, burn eyes, lacrimation (discharge of tears), conjunctivitis; erythema (skin redness) eyelids, blepharospasm; irritation throat, cough, chest tightness; headache; erythema (skin redness), skin vesiculation Target Organs: Eyes, skin, respiratory system (NIOSH, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Rapid support of respiration and circulation is essential to successful treatment of cyanide intoxication. Massive cyanide overdoses have survived with only good supportive care. Immediate attention should be directed toward assisted ventilation, administration of 100% oxygen, insertion of intravenous lines, and institution of cardiac monitoring. Obtain an arterial blood gas immediately and correct any severe metabolic acidosis (pH below 7.15). Oxygen (100%) should be used routinely in moderate or severely symptomatic patients even in the presence of a normal pO2, since 100% O2 increases O2 delivery, may reactivate cyanide-inhibited mitochondrial enzymes, and potentiates the effect of thiosulfate. Avoid mouth to mouth resuscitation during CPR in order to prevent self poisoning. Cyanides
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
5.2 Specific hazards arising from the chemical
Flash point data for this chemical are not available, but it is probably combustible. (NTP, 1992)
5.3 Special protective actions for fire-fighters
Use powder, carbon dioxide.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Vacuum spilled material with specialist equipment. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
6.2 Environmental precautions
Vacuum spilled material with specialist equipment. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance.
6.3 Methods and materials for containment and cleaning up
1. ventilate area of spill. 2. for small quantities, sweep onto paper or other suitable material, place in appropriate container & burn in safe place (such as fume hood). large quantities may be reclaimed; however, if this is not practical, dissolve in flammable solvent (such as alcohol) & atomize in suitable combustion chamber equipped with appropriate effluent gas cleaning device. 3. decontaminate area of spill: (a) by washing with a 5% solution of sodium hydroxide in 50/50 ethyl alcohol/water; or (b) by adding flake sodium hydroxide to a solution or slurry of the spill in isopropyl alcohol; or (c) by covering the spill with a 10% solution of sodium hydroxide in 50/50 isopropyl alcohol/water & letting stand 20 minutes before flushing with water.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. Closed system, dust explosion-proof electrical equipment and lighting. Prevent deposition of dust. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs. Keep in a well-ventilated room.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 0.05 ppm as STEL; (skin); A4 (not classifiable as a human carcinogen)
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles or face shield.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use local exhaust.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | PHYSICAL DESCRIPTION: White crystalline solid or light beige powder. Odor of pepper. (NTP, 1992) |
|---|---|
| Colour | White crystalline solid |
| Odour | Pepper-like odor. |
| Melting point/freezing point | 95ºC |
| Boiling point or initial boiling point and boiling range | 310-315ºC |
| Flammability | Combustible Solid |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 148ºC |
| Auto-ignition temperature | no data available |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | 1 to 5 mg/mL at 61° F (NTP, 1992) |
| Partition coefficient n-octanol/water | no data available |
| Vapour pressure | 0.000527mmHg at 25°C |
| Density and/or relative density | 1.296 g/cm3 |
| Relative vapour density | 6.52 (NTP, 1992) (Relative to Air) |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Reacts with strong bases and strong acids. This produces ammonia. Decomposes on burning. This produces toxic fumes including hydrogen chloride, hydrogen cyanide and nitrogen oxides. Reacts violently with strong oxidants. This generates fire and explosion hazard.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
O-CHLOROBENZYLIDENE MALONONITRILE may react with strong oxidizers. (NTP, 1992)
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizers.
10.6 Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of hydrogen chloride, nitrogen oxides and cyanides.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat (male) oral 1366 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4: Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
Lachrymation. The substance is severely irritating to the eyes, skin and respiratory tract. The substance may cause effects on the lungs.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 Rainbow trout 1.28 mg/l/12 hr. /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
An estimated BCF of 30 was calculated for 2-chlorobenzalmalononitrile(SRC), using an estimated log Kow of 2.76(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.
12.4 Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc for 2-chlorobenzalmalononitrile can be estimated to be 1700(SRC). According to a classification scheme(2), this estimated Koc value suggests that 2-chlorobenzalmalononitrile is expected to have low mobility in soil.
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN2647 (For reference only, please check.) | IMDG: UN2647 (For reference only, please check.) | IATA: UN2647 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: MALONONITRILE (For reference only, please check.) | IMDG: MALONONITRILE (For reference only, please check.) | IATA: MALONONITRILE (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 (For reference only, please check.) | IMDG: 6.1 (For reference only, please check.) | IATA: 6.1 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: II (For reference only, please check.) | IMDG: II (For reference only, please check.) | IATA: II (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: Yes | IMDG: Yes | IATA: Yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| [(2-chlorophenyl)methylene]malononitrile | [(2-chlorophenyl)methylene]malononitrile | 2698-41-1 | 220-278-9 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Not Listed. | ||
| Vietnam National Chemical Inventory | Not Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Not Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The occupational exposure limit value should not be exceeded during any part of the working exposure.
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
2-Chlorobenzylidenemalononitrile is included in Organic Reagents category.
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