4-tert-Butyltoluene Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | 4-tert-butyltoluene |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Benzene, 1-(1,1-dimethylethyl)-4-methyl-; 1-tert-butyl-4-methylbenzene |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Industrial and scientific research uses. |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 2, Inhalation
Reproductive toxicity, Category 2
Specific target organ toxicity â single exposure, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |  |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H302 Harmful if swallowed H319 Causes serious eye irritation H330 Fatal if inhaled H361 Suspected of damaging fertility or the unborn child H372 Causes damage to organs through prolonged or repeated exposure H401 Toxic to aquatic life H411 Toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment. |
| Response | P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P320 Specific treatment is urgent (see ... on this label). P318 IF exposed or concerned, get medical advice. P308+P316 IF exposed or concerned: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P391 Collect spillage. |
| Storage | P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 4-tert-butyltoluene | 4-tert-butyltoluene | 98-51-1 | 202-675-9 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Half-upright position. Refer immediately for medical attention.
Following skin contact
Rinse and then wash skin with water and soap.
Following eye contact
Rinse with plenty of water for several minutes (remove contact lenses if easily possible).
Following ingestion
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Exposure Routes: inhalation, ingestion, skin and/or eye contact Symptoms: Irritation eyes, skin; dry nose, throat; headache; low blood pressure, tachycardia, abnormalities cardiovascular system stress; central nervous system, hematopoietic depression; metallic taste; liver, kidney injury Target Organs: Eyes, skin, respiratory system, cardiovascular system, central nervous system, bone marrow, liver, kidneys (NIOSH, 2016)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Flush eyes with water. Wash off contaminated areas of body with soap and water. Gastric lavage (stomach wash), if swallowed, followed by saline catharsis.
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or halon extinguisher. (NTP, 1992)
5.2 Specific hazards arising from the chemical
This chemical is combustible. (NTP, 1992)
5.3 Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam, dry powder, carbon dioxide.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: self-contained breathing apparatus. Do NOT let this chemical enter the environment. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
Absorb on paper. Evaporate on a glass or an iron dish in hood. Burn the paper.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames. Above 63°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from food and feedstuffs and strong oxidants. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
TLV: 1 ppm as TWA
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety spectacles or eye protection in combination with breathing protection.
Skin protection
Protective gloves.
Respiratory protection
Use ventilation, local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | Liquid. |
|---|---|
| Colour | Clear, colourless. |
| Odour | DISTINCT AROMATIC ODOR |
| Melting point/freezing point | -52 °C. |
| Boiling point or initial boiling point and boiling range | 193 °C. Atm. press.:1 013 hPa. |
| Flammability | Class IIIA Combustible Liquid: Fl.P. at or above 140°F and below 200°F. |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 58.3 °C. Atm. press.:1 013.25 hPa. |
| Auto-ignition temperature | 510 °C. Atm. press.:1 013.25 hPa. |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | dynamic viscosity (in mPa s) = 1.677. Temperature:0.0°C. |
| Solubility | less than 1 mg/mL at 63° F (NTP, 1992) |
| Partition coefficient n-octanol/water | log Pow = 4.4. |
| Vapour pressure | 1.3 hPa. Temperature:30 °C. |
| Density and/or relative density | 0.86 g/cm³. Temperature:20 °C. |
| Relative vapour density | 4.62 (AIR= 1) |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on burning. This produces toxic fumes. Reacts with strong oxidants. This generates fire and explosion hazard.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
Flammable. Moderately dangerous fire risk.As a result of flow, agitation, etc., electrostatic charges can be generated.P-TERT-BUTYLTOLUENE may react with oxidizing materials. (NTP, 1992)
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Oxidizers.
10.6 Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - ca. 1 550 mg/kg bw. Remarks:Original value: LD50 = 1.8 +/- 0.14 ml/kg bw.
- Inhalation: LC50 - rat (female) - ca. 1.5 mg/L air.
- Dermal: LD50 - rabbit - ca. 16 880 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. Exposure far above the OEL could cause lowering of consciousness.
STOT-repeated exposure
The substance may have effects on the central nervous system. This may result in tissue lesions.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50 - Cyprinus carpio - 2 mg/L - 96 h. Remarks:Concentrations are given as arithm. means of calculated test concentrations and measured test concentrations after 24 hours.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 3.2 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 5.6 mg/L - 72 h.
- Toxicity to microorganisms: EC0 - Pseudomonas putida - >= 1 000 mg/L - 5 h. Remarks:Respiration rate.
12.2 Persistence and degradability
Using a standard dilution method over a 5-day inoculation period and a seed from an effluent of a biological sanitary waste treatment plant, 4-t-butyltoluene was found to have a 2% theoretical BOD when the seed was not adapted and 6% theoretical BOD when the seed was adapted(1).
12.3 Bioaccumulative potential
Based upon a reported water solubility of 5.5 ppm at 25 deg C(1), the BCF for 4-t-butyltoluene can be estimated to be 236 from a recommended regression-derived equation(2,SRC). This estimated BCF indicates that some bioconcentration in aquatic organisms may occur(SRC).
12.4 Mobility in soil
Based upon a reported water solubility of 5.5 ppm at 25 deg C(1), the Koc for 4-t-butyltoluene can be estimated to be 1700 from a linear regression-derived equation(2,SRC). Using a structure estimation method based on molecular connectivity indexes, the Koc for 4-t-butyltoluene can be estimated to be 1900(3). These estimated Koc values indicate that 4-t-butyltoluene will have low mobility in soil(4).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN2667 (For reference only, please check.) | IMDG: UN2667 (For reference only, please check.) | IATA: UN2667 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: BUTYLTOLUENES (For reference only, please check.) | IMDG: BUTYLTOLUENES (For reference only, please check.) | IATA: BUTYLTOLUENES (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 6.1 (For reference only, please check.) | IMDG: 6.1 (For reference only, please check.) | IATA: 6.1 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: III (For reference only, please check.) | IMDG: III (For reference only, please check.) | IATA: III (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: Yes | IMDG: Yes | IATA: Yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 4-tert-butyltoluene | 4-tert-butyltoluene | 98-51-1 | 202-675-9 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The odour warning when the exposure limit value is exceeded is insufficient.
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
4-tert-Butyltoluene is included in Perfuming category.
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