Diethyl phthalate Safety Data Sheets

Not classified.

If inhaled

Following skin contact

Following eye contact

Following ingestion

Symptoms unlikely from any form of exposure. (USCG, 1999)

Special Hazards of Combustion Products: Irritating vapors of unburned chemical may form in fire. (USCG, 1999)

Use alcohol-resistant foam, powder, carbon dioxide.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

Environmental considerations-land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Storage temp: ambient; venting: open.

Occupational Exposure limit values

Biological limit values

Eye/face protection

Skin protection

Respiratory protection

Thermal hazards

Decomposes on heating and on burning. This produces toxic fumes and gases (phthalic anhydride - see ICSC 0315). Attacks some plastics.

Stable to light

CombustibleDIETHYL PHTHALATE is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. Can generate electrostatic charges. [Handling Chemicals Safely 1980. p. 250].

no data available

May attack some forms of plastics.

When heated to decomp it emits acrid smoke and irritating fumes.

Acute toxicity

• Oral: LD50 - rat - 8.2 mL/kg bw.
• Inhalation: LC50 Rat inhalation >4.64 mg/L for 6 hr
• Dermal: no data available

Skin corrosion/irritation

Serious eye damage/irritation

Respiratory or skin sensitization

Germ cell mutagenicity

Carcinogenicity

Reproductive toxicity

STOT-single exposure

STOT-repeated exposure

Aspiration hazard

• Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, young of year, weight 0.32-1.2 g); Conditions: freshwater, static, 21-23 deg C, pH 6.5-7.9, hardness 32-48 mg/L CaCO3, alkalinity 28-34 mg/L CaCO3, conductivity 93-190 umhos/cm, dissolved oxygen 0.3-9.7 mg/L; Concentration: 120000 ug/L for 24 hr /> or = 80% purity
• Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 52 mg/L - 24 h.
• Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - 85.6 mg/L - 96 h.
• Toxicity to microorganisms: no data available

AEROBIC: The aerobic half-life of diethyl phthalate in natural fresh water was estimated as 3 days(1). Diethyl phthalate was found to degrade to ethyl methyl phthalate, dimethyl phthalate, methyl phthalate and ethyl phthalate when co-contaminated with methanol(2). A shake flask experiment using microorganisms isolated from a municipal sludge resulted in complete aerobic degradation of 400 mg/L of diethyl phthalate in approximately 35 hours, 200 mg/L in 25 hours, 140 mg/L in 22 hours and 75 mg/L in 18 hours(3). Diethyl phthalate was completely degraded by Rhine River water at 20 deg C in a 3 day die-away test(4). Diethyl phthalate was 87-92% degraded in 10-50 days at 25 deg C from a concn of 100 mg/L using 30 mg/L activated sludge(5). Electrolytic respirometer studies have shown that diethyl phthalate is readily biodegradable under aerobic conditions(6-8). Diethyl phthalate had aerobic aquatic half-lives of 0.39 days in a river die-away test, 4.33 days in MITI test, and 0.71 days using microcosm periphlton, and an aerobic soil half-life of 1.83 days agitated in aqueous suspension(9).

Bluegill sunfish exposed to 9.42 ug/L of diethyl phthalate for 21 days had a measured BCF of 117(1). According to a classification scheme(2), this BCF value suggests that bioconcentration in aquatic organisms is high(SRC). An experimental log BCF of 2.07 was measured in clams(3).

A Koc value of diethyl phthalate of 1,726 was measured in podzol soil at pH 2.8 and 4.85% carbon, a value of 704 in alfisol soil at pH 6.7 and 1.25% carbon, a value of 320 in sediment at pH 7.1 and 1.58% carbon(1). An experimental log Koc of 1.99 was determined from unsaturated soil columns at pH 4.8(2). A Koc value of 69 was determined from measurements on soil samples from Broome County, NY(3). According to a classification scheme(4), these Koc values suggest that diethyl phthalate is expected to have low to high mobility in soil.

no data available

Product

Contaminated packaging

no data available

no data available

Information on revision

Abbreviations and acronyms

• CAS: Chemical Abstracts Service
• ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
• RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
• IMDG: International Maritime Dangerous Goods
• IATA: International Air Transportation Association
• TWA: Time Weighted Average
• STEL: Short term exposure limit
• LC50: Lethal Concentration 50%
• LD50: Lethal Dose 50%
• EC50: Effective Concentration 50%

References

• IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
• HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
• IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
• eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
• CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
• ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
• ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
• Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
• ECHA - European Chemicals Agency, website: https://echa.europa.eu/