Hexachlorobenzene Safety Data Sheets

SAFETY DATA SHEETS

According to the UN GHS revision 8

Version: 1.0

Creation Date: July 15, 2019

Revision Date: July 15, 2019

SECTION 1: Identification

1.1 GHS Product identifier

Product name	Hexachlorobenzene

1.2 Other means of identification

Product number	-
Other names	Benzene, hexachloro-; perchlorobenzene; HCB

1.3 Recommended use of the chemical and restrictions on use

Identified uses	Pesticides (chemicals used for killing pests, such as rodents, insects, or plants)
Uses advised against	no data available

1.4 Supplier's details

Company	Echemi.com
Address	Echemi.com
Telephone	Echemi.com

1.5 Emergency phone number

Emergency phone number	Echemi.com
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

SECTION 2: Hazard identification

2.1 Classification of the substance or mixture

Carcinogenicity, Category 1B

Specific target organ toxicity â repeated exposure, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H350 May cause cancer H372 Causes damage to organs through prolonged or repeated exposure H410 Very toxic to aquatic life with long lasting effects
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment.
Response	P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

2.3 Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
Hexachlorobenzene	Hexachlorobenzene	118-74-1	204-273-9	100%

SECTION 4: First-aid measures

4.1 Description of necessary first-aid measures

If inhaled

Fresh air, rest. Refer for medical attention.

Following skin contact

Rinse and then wash skin with water and soap. Refer for medical attention .

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Harmful by dust inhalation or if swallowed. Irritating to eyes, skin and mucous membranes. Prolonged periods of ingestion may cause cutaneous porphyria. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Lindane and related compounds

SECTION 5: Fire-fighting measures

5.1 Suitable extinguishing media

Use water spray, foam, powder, carbon dioxide.

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: They contain highly toxic chloride fumes. Behavior in Fire: Produces highly toxic chloride fumes. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Use water spray, foam, powder, carbon dioxide.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

6.2 Environmental precautions

Personal protection: chemical protection suit and particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

6.3 Methods and materials for containment and cleaning up

Absorb the spills with paper towels or like materials. Place in hood to evaporate followed by burning the towel. Dissolve in a combustible solvent. Scatter the spray of the solution into the furnace with after burners and alkali scrubber.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs. Well closed.Separated from food and feedstuffs. Well closed.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

TLV: 0.002 mg/m3, as TWA; (skin); A3 (confirmed animal carcinogen with unknown relevance to humans).MAK: skin absorption (H); carcinogen category: 4; pregnancy risk group: D

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear face shield or eye protection in combination with breathing protection.

Skin protection

Protective gloves. Protective clothing.

Respiratory protection

Use local exhaust or breathing protection.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

Physical state	Hexachlorobenzene is a white crystalline substance. Insoluble in water and denser than water. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.
Colour	White needles
Odour	no data available
Melting point/freezing point	228-231ÂºC
Boiling point or initial boiling point and boiling range	332ÂºC
Flammability	Combustible.
Lower and upper explosion limit/flammability limit	no data available
Flash point	242ÂºC
Auto-ignition temperature	no data available
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	no data available
Solubility	less than 1 mg/mL at 68Â° F (NTP, 1992)
Partition coefficient n-octanol/water	log Kow = 5.73
Vapour pressure	0.000463mmHg at 25Â°C
Density and/or relative density	1.5691
Relative vapour density	9.8 (NTP, 1992) (Relative to Air)
Particle characteristics	no data available

SECTION 10: Stability and reactivity

10.1 Reactivity

Decomposes on heating. This produces toxic fumes.

10.2 Chemical stability

Very stable, even to acids and bases.

10.3 Possibility of hazardous reactions

Not flammable or combustible.HEXACHLOROBENZENE reacts violently with dimethylformamide. (NTP, 1992).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Dimethyl formamide and hexachlorobenzene react violently above 65 deg c.

10.6 Hazardous decomposition products

Dangerous; When heated to decomposition, emits toxic fumes of /hydrogen chloride/.

SECTION 11: Toxicological information

Acute toxicity

Oral: LD50 Rat oral 3500 mg/kg
Inhalation: no data available
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

NTP: Reasonably anticipated to be a human carcinogen

Reproductive toxicity

One human study reported abnormal physical development in young children who ingested contaminated bread during a 4-year poisoning incident. Hexachlorobenzene has been found to decrease the survival rates of newborn animals and to cross the placenta and accumulate in fetal tissue in several animal species. Neurological, teratogenic, liver, and immune system effects have been reported in the offspring of animals orally exposed to hexachlorobenzene while they were pregnant.

STOT-single exposure

no data available

STOT-repeated exposure

The substance may have effects on the liver and nervous system. This may result in impaired functions of organs and skin lesions. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction.

Aspiration hazard

Evaporation at 20Â°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnow) weight 0.7 g; Conditions: static bioassay, 20 deg C; Concentration: 22 mg/L for 96 hr @ 20 deg C (95% confidence limit) /technical 80-96%
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

Little to no biodegradation was noted in biodegradation screening tests(1,3,4), in activated sludge(2,5), or in soil(6-8). Measurement of CO2 evolution from suspended soil cultures over a 14-day incubation period were as follows: 0.4% under aerobic conditions, 0.2% under anaerobic conditions(9).

12.3 Bioaccumulative potential

BCF values of 2,700 to 4,800 were measured in carp exposed to 10 ug/L of hexachlorobenzene during an 8 week incubation period and BCF values of 1,600 to 3,900 were measured in carp exposed to 1 ug/L of hexachlorobenzene during an 8 week incubation period(1). Log BCF values in rainbow trout (Salmo gairdneri) were given as 3.7-4.3(2-4) and in fathead minnows (Pimephales promelas) and sunfish (Lepomis cyanellus) log BCF values of 4.21 and 4.34, respectively, were reported(3). After an 8-week exposure period of carp (Cyprinus carpio) to concentrations of 0.5 and 0.05 ug/L of hexachlorobenzene, the BCFs were 11,000-27,000 and 6,000-30,000, respectively(5). According to a classification scheme(6), these BCF values suggest that bioconcentration in aquatic organisms is very high, provided the compound is not metabolized by the organism(SRC).

12.4 Mobility in soil

A log Koc value of 5.5 (Koc of 3.2X10+5) was reported for hexachlorobenzene in freshwater river sediment(1). A log Koc value of 4.9 (Koc of 7.9X10+4) was reported for hexachlorobenzene in sediment obtained from the Ise Bay, Japan(2). Measured log Koc values of 3.6 (Koc of 4X10+3)(3) and 4.0 (Koc of 1X10+4)(4) were reported in soils. Log Koc values of 6.42 and 5.56 (Koc values of 2.6X10+6 and 3.6X10+5) were determined for two sediment layers from a lake(5). Hexachlorobenzene has measured log Koc value of 3.99 (Koc of 9.8X10+3) reported for soils(6). Hexachlorobenzene was found to desorb very slowly from sediment in water(7). According to a recommended classification scheme(8), these Koc values suggest that hexachlorobenzene is expected to be immobile in soil(SRC).

12.5 Other adverse effects

no data available

SECTION 13: Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

14.1 UN Number

ADR/RID: UN2729 (For reference only, please check.)

IMDG: UN2729 (For reference only, please check.)

IATA: UN2729 (For reference only, please check.)

14.2 UN Proper Shipping Name

ADR/RID: HEXACHLOROBENZENE (For reference only, please check.)

IMDG: HEXACHLOROBENZENE (For reference only, please check.)

IATA: HEXACHLOROBENZENE (For reference only, please check.)

14.3 Transport hazard class(es)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

14.4 Packing group, if applicable

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

14.5 Environmental hazards

ADR/RID: Yes

IMDG: Yes

IATA: Yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
Hexachlorobenzene	Hexachlorobenzene	118-74-1	204-273-9
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Listed.
New Zealand Inventory of Chemicals (NZIoC)			Not Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.
Korea Existing Chemicals List (KECL)			Not Listed.

SECTION 16: Other information

Information on revision

Creation Date	July 15, 2019
Revision Date	July 15, 2019

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Other Information

Depending on the degree of exposure, periodic medical examination is suggested.Do NOT take working clothes home.

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Hexachlorobenzene is included in Hydrocarbons and Derivatives category.