p-Cymene Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | p-cymene |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Benzene, 1-methyl-4-(1-methylethyl)-; 4-Isopropyltoluene; p-Isopropyltoluene (p-Cymene) |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Food additives -> Flavoring Agents |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Flammable liquids, Category 3
Aspiration hazard, Category 1
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H226 Flammable liquid and vapour H304 May be fatal if swallowed and enters airways H315 Causes skin irritation H319 Causes serious eye irritation |
| Precautionary statement(s) | |
| Prevention | P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. |
| Response | P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P316 IF SWALLOWED: Get emergency medical help immediately. P331 Do NOT induce vomiting. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. |
| Storage | P403+P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| p-cymene | p-cymene | 99-87-6 | 202-796-7 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap. Wear protective gloves when administering first aid.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Do NOT induce vomiting. Rest. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
Inhalation causes impairment of coordination, headache. Contact with liquid causes mild irritation of eyes and skin. Ingestion causes irritation of mouth and stomach. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped or safely confined. Use water in flooding quantities as fog. Solid streams of water may spread fire. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide. Cymenes
5.2 Specific hazards arising from the chemical
Excerpt from ERG Guide 130 [Flammable Liquids (Water-Immiscible / Noxious)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)
5.3 Special protective actions for fire-fighters
Use powder, AFFF, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance.
6.2 Environmental precautions
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance.
6.3 Methods and materials for containment and cleaning up
Environmental considerations: Air spill: Apply water spray or mist to knock down vapors. Cymenes
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 47°C use a closed system, ventilation and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding). Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Fireproof.Safe storage: Fireproof.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
| Component | p-cymene | |||
|---|---|---|---|---|
| CAS No. | 99-87-6 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Belgium | 20 | 100 | Â | Â |
| Denmark | 25 | 135 | 50 | 270 |
| Sweden | 25 | 140 | 35 (1) | 190 (1) |
| Remarks | ||||
| Sweden | (1) 15 minutes average value | |||
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety spectacles.
Skin protection
Protective gloves.
Respiratory protection
Use ventilation.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | P-cymene is a colorless liquid with a mild pleasant odor. Floats on water. (USCG, 1999) |
|---|---|
| Colour | Colorless transparent liquid |
| Odour | Sweetish aromatic odor |
| Melting point/freezing point | 26°C(lit.) |
| Boiling point or initial boiling point and boiling range | 176-178°C(lit.) |
| Flammability | Flammable. |
| Lower and upper explosion limit/flammability limit | Lower flammable limit: 0.7% at 212 deg F (100 deg C) by volume; Upper flammable limit: 5.6% by volume |
| Flash point | 47°C |
| Auto-ignition temperature | 817°F |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | In water, 23.4 mg/L at 25 deg C |
| Partition coefficient n-octanol/water | log Kow = 4.10 |
| Vapour pressure | 1.5 mm Hg ( 20 °C) |
| Density and/or relative density | 0.86g/mLat 25°C(lit.) |
| Relative vapour density | 4.62 (vs air) |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Reacts with oxidants. Attacks rubber.
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
Flammable liquid.The vapour is heavier than air.Vigorous reactions, sometimes amounting to explosions, can result from the contact between aromatic hydrocarbons, such as CYMENE, and strong oxidizing agents. They can react exothermically with bases and with diazo compounds. Substitution at the benzene nucleus occurs by halogenation (acid catalyst), nitration, sulfonation, and the Friedel-Crafts reaction.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Reacts with oxidants. Attacks rubber.
10.6 Hazardous decomposition products
When heated to decomposition it emits acrid smoke and fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 4750 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and skin. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking.
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill); Conditions: freshwater, static; Concentration: 44000 ug/L for 96 hr /formulation
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water Flea) age < or =24 hr; Conditions: freshwater, static, 22 deg C, pH 7.4-9.4, dissolved oxygen 6.5-9.1 mg/L; Concentration: 9400 ug/L for 24 hr (95% confidence interval: 7900-11000 ug/L) /> or =80% purity
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae); Conditions: freshwater, static; Concentration: 49000 ug/L for 96 hr; Effect: population, chlorophyll A concentration /formulation
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: A batch system die-away test using artificial seawater, a 10-day incubation period, and an inoculum of coastal water from the North Sea found p-cymene to undergo moderate bio-oxidation (actual rates not reported)(1). p-Cymene, present at 100 mg/L, reached 83-95% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(2,3) which classifies p-cymene as readily biodegradable(3).
12.3 Bioaccumulative potential
An estimated BCF of 236 was calculated for p-cymene(SRC), using a log Kow of 4.10(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is high, provided the compound is not metabolized by the organism(SRC).
12.4 Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of p-cymene can be estimated to be 1120(SRC). According to a classification scheme(2), this estimated Koc value suggests that p-cymene is expected to have low mobility in soil.
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN2046 (For reference only, please check.) | IMDG: UN2046 (For reference only, please check.) | IATA: UN2046 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: CYMENES (For reference only, please check.) | IMDG: CYMENES (For reference only, please check.) | IATA: CYMENES (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 3 (For reference only, please check.) | IMDG: 3 (For reference only, please check.) | IATA: 3 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: III (For reference only, please check.) | IMDG: III (For reference only, please check.) | IATA: III (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: No | IMDG: No | IATA: No |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| p-cymene | p-cymene | 99-87-6 | 202-796-7 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
p-Cymene is included in Fragrance Ingredient category.
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