Perfluorooctanoic acid Safety Data Sheets
SAFETY DATA SHEETS
According to the UN GHS revision 8
SECTION 1: Identification
1.1 GHS Product identifier
| Product name | Pentadecafluorooctanoic acid |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | A 5717; [14C]-Perfluorooctanoic acid; Eftop EF 201 |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | Intermediates |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
| Company | Echemi.com |
|---|---|
| Address | Echemi.com |
| Telephone | Echemi.com |
1.5 Emergency phone number
| Emergency phone number | Echemi.com |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Serious eye damage, Category 1
Acute toxicity - Category 4, Inhalation
Carcinogenicity, Category 2
Reproductive toxicity, Additional category for effects on or via lactation
Specific target organ toxicity â repeated exposure, Category 1
Reproductive toxicity, Category 1B
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H302 Harmful if swallowed H318 Causes serious eye damage H332 Harmful if inhaled H351 Suspected of causing cancer H362 May cause harm to breast-fed children H372 Causes damage to organs through prolonged or repeated exposure |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P263 Avoid contact during pregnancy and while nursing. |
| Response | P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell. |
| Storage | P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal. |
2.3 Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| Pentadecafluorooctanoic acid | Pentadecafluorooctanoic acid | 335-67-1 | 206-397-9 | 100% |
SECTION 4: First-aid measures
4.1 Description of necessary first-aid measures
If inhaled
Fresh air, rest. Refer for medical attention.
Following skin contact
Remove contaminated clothes. Rinse and then wash skin with water and soap.
Following eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Following ingestion
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
no data available
4.3 Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Poisons A and B
SECTION 5: Fire-fighting measures
5.1 Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
5.2 Specific hazards arising from the chemical
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of fire and explosion on contact with bases, oxidants or reducing agents.
5.3 Special protective actions for fire-fighters
Use water spray, carbon dioxide, dry powder, foam.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
6.2 Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
6.3 Methods and materials for containment and cleaning up
ACCIDENTAL RELEASE MEASURES: Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust; Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains; Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
SECTION 7: Handling and storage
7.1 Precautions for safe handling
NO contact with incompatible substances. See Chemical Dangers. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
7.2 Conditions for safe storage, including any incompatibilities
Separated from strong oxidants, strong bases, strong acids, strong reducing agents and food and feedstuffs.Keep container tightly closed in a dry and well-ventilated place.
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
MAK: (inhalable fraction): 0.005 mg/m3; peak limitation category: II(8); skin absorption (H); carcinogen category: 4; pregnancy risk group: C
Biological limit values
no data available
8.2 Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Wear safety goggles or eye protection in combination with breathing protection if powder.
Skin protection
Protective gloves. Protective clothing.
Respiratory protection
Use local exhaust or breathing protection.
Thermal hazards
no data available
SECTION 9: Physical and chemical properties and safety characteristics
| Physical state | OtherSolid |
|---|---|
| Colour | White to off-white powder |
| Odour | no data available |
| Melting point/freezing point | 56°C(lit.) |
| Boiling point or initial boiling point and boiling range | 189°C/736mmHg(lit.) |
| Flammability | Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit/flammability limit | no data available |
| Flash point | 122°C(lit.) |
| Auto-ignition temperature | no data available |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | no data available |
| Solubility | In water, 2290 mg/L at 24 deg C |
| Partition coefficient n-octanol/water | log Kow = 4.81 (est) |
| Vapour pressure | 3.16X10-2 mm Hg at 25 deg C |
| Density and/or relative density | 1.7 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
SECTION 10: Stability and reactivity
10.1 Reactivity
Decomposes on heating above 300°C . Decomposes on burning. This produces toxic gases including hydrogen fluoride. The solution is a weak acid. Reacts with bases, oxidants and reducing agents. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001).
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
No data.Decomposes on heating above 300°C . This produces toxic and corrosive gases including hydrogen fluoride (See ICSC 0283). The solution is a weak acid. Reacts with bases, oxidants and reducing agents. This produces flammable/explosive gas (hydrogen - see ICSC 0001). Attacks many metals.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Incompatible materials: Bases, Oxidizing agents, Reducing agents
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic vapors of /flourine/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: no data available
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract.
STOT-repeated exposure
The substance may have effects on the liver and immune system. This substance is possibly carcinogenic to humans. May cause toxicity to human reproduction or development.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
12.1 Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) age <24 hr neonate; Conditions: freshwater, static, 20 deg C; Concentration: 0.531 mM for 24 hr (95% confidence interval: 0.506-0.555 mM); Effect: intoxication, immobilization /96% purity
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green Algae) 3000000 cells/mL; Conditions: freshwater, static; Concentration: 1.807 mM for 4.5 hr (95% confidence interval: 1.76-1.86 mM); Effect: population, decreased photosynthesis /96% purity
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: Perfluorooctanoic acid, present at 100 mg/L, reached 5% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Organic fluorochemical compounds, such as perfluorooctanoic acid, are expected to be resistant to biodegradation(2). A related compound, perfluorooctane sulfonic acid, was found to not degrade under aerobic or anaerobic conditions(3).
12.3 Bioaccumulative potential
BCF values of 3.1 and 9.4 were measured in fish using carp (Cyprinus carpio) which were exposed to 5 and 50 ug/L, respectively, perfluorooctanoic acid over a 4-week period(1). According to a classification scheme(2), these BCF values suggest that bioconcentration in aquatic organisms is low(SRC). Perfluorinated carboxylates with seven carbons or less may have low biomagnification potential in the food chain(3). The bioconcentration factors of perfluorooctanoic acid in wild turtles (Trachemys scriptaelegans and Chinemys reevesii) from the Ai River, Japan ranged from 0.8 to 15.8 (serum/water concentrations)(4).
12.4 Mobility in soil
The log Koc of perfluorooctanoic acid was reported as 1.92-2.59 measured in three soils(1). According to a classification scheme(2), these log Koc values suggest that perfluorooctanoic acid is expected to have high to moderate mobility in soil. Based on a variety of conditions, pKa values of perfluorooctanoic acid have been reported as -0.5 to 4.2(3), indicating that this compound will exist entirely in anion form and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). The log Koc and log Kd is 10 and 21 in sediment samples collected from Etobicoke Creek, Canada were reported as 0.88-1.85 and 0.16-1.44, respectively(5). The log Kd in 19 sediment samples collected from major rivers, lakes and canals in The Netherlands, May to Aug 2007 was 1.19-2.85(6). The log Koc and log Kd were reported as 2.6-4.2 and 1.3-2.8, respectively, in 32 sediment samples collected along the Haihe River, China; samples were collected April to May 2010(7). The average and median values for log Koc in 17 sediments were both 2.1(8).
12.5 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
14.1 UN Number
| ADR/RID: UN3261 (For reference only, please check.) | IMDG: UN3261 (For reference only, please check.) | IATA: UN3261 (For reference only, please check.) |
14.2 UN Proper Shipping Name
| ADR/RID: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (For reference only, please check.) | IMDG: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (For reference only, please check.) | IATA: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S. (For reference only, please check.) |
14.3 Transport hazard class(es)
| ADR/RID: 8 (For reference only, please check.) | IMDG: 8 (For reference only, please check.) | IATA: 8 (For reference only, please check.) |
14.4 Packing group, if applicable
| ADR/RID: I (For reference only, please check.) | IMDG: I (For reference only, please check.) | IATA: I (For reference only, please check.) |
14.5 Environmental hazards
| ADR/RID: No | IMDG: No | IATA: No |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| Pentadecafluorooctanoic acid | Pentadecafluorooctanoic acid | 335-67-1 | 206-397-9 |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Not Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
| Korea Existing Chemicals List (KECL) | Listed. | ||
SECTION 16: Other information
Information on revision
| Creation Date | July 15, 2019 |
|---|---|
| Revision Date | July 15, 2019 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
Perfluorooctanoic acid is included in Bulk Drug Intermediates category.
Buy Perfluorooctanoic acid of different grades for your demands from various manufactures and traders.
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