Polyethylene glycol monobutyl ether Safety Data Sheets

Characteristics

Products for Sale

SAFETY DATA SHEETS

According to the UN GHS revision 8

Version: 1.0

Creation Date: July 15, 2019

Revision Date: July 15, 2019

SECTION 1: Identification

1.1 GHS Product identifier

Product name	Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	Food additives -> Flavoring Agents
Uses advised against	no data available

1.4 Supplier's details

Company	Echemi.com
Address	Echemi.com
Telephone	Echemi.com

1.5 Emergency phone number

Emergency phone number	Echemi.com
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

SECTION 2: Hazard identification

2.1 Classification of the substance or mixture

Serious eye damage, Category 1

2.2 GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H318 Causes serious eye damage
Prevention	P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help.
Storage	none
Disposal	none

2.3 Other hazards which do not result in classification

no data available

SECTION 3: Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-	Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-	9004-77-7	500-012-0	100%

SECTION 4: First-aid measures

4.1 Description of necessary first-aid measures

If inhaled

Fresh air, rest. Refer for medical attention.

Following skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

Following eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Following ingestion

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Vapors irritate eyes and nose. Ingestion or skin contact causes headache, nausea, vomiting, dizziness. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Ethylene glycol, glycols, and related compounds

SECTION 5: Fire-fighting measures

5.1 Suitable extinguishing media

Carbon dioxide or dry chemical for small fires; alcohol-type foam for large fires.

5.2 Specific hazards arising from the chemical

Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. Substance may be transported hot. For hybrid vehicles, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. If molten aluminum is involved, refer to ERG Guide 169. (ERG, 2016)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.

6.2 Environmental precautions

Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.

6.3 Methods and materials for containment and cleaning up

Ventilate area of spill or leak. For small quantities, absorb on paper towels. Evaporate in safe place (such as fume hood). Allow sufficient time for evaporating vapors to completely clear hood ductwork. Burn paper in suitable location away from combustible materials. Large quantities can be collected and atomized in suitable combustion chamber. Waste disposal: By absorbing it in vermiculite, dry sand, earth or similar material and disposing in secured sanitary landfill; By atomizing in suitable combustion chamber.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

7.2 Conditions for safe storage, including any incompatibilities

Separated from strong oxidants and food and feedstuffs. Cool. Keep in the dark.Separated from strong oxidants, food and feedstuffs. Cool. Keep in the dark

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

Component	Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-
CAS No.	9004-77-7
	Recommended Exposure Limit: 10 Hour Time-Weighted Average: 5 ppm (24 mg/cu m). Skin designation.

Biological limit values

no data available

8.2 Appropriate engineering controls

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).

Skin protection

Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.

Thermal hazards

no data available

SECTION 9: Physical and chemical properties and safety characteristics

Physical state	Ethylene glycol monobutyl ether is a colorless liquid with a mild, pleasant odor. Less dense than water. Flash point 160Â°F. Irritates skin and eyes and may be toxic by ingestion. Used as a solvent and to make paints and varnish.
Colour	Colorless liquid
Odour	Mild, ether-like odor
Melting point/freezing point	-94Â° F (NTP, 1992)
Boiling point or initial boiling point and boiling range	340Â° F at 743 mm Hg (NTP, 1992)
Flammability	Class IIIA Combustible Liquid: Fl.P. at or above 140Â°F and below 200Â°F.
Lower and upper explosion limit/flammability limit	Lower flammable limit: 1.1% by volume @ 93 deg C; Upper flammable limit:12.7% by volume @ 135 deg C
Flash point	141Â° F (NTP, 1992)
Auto-ignition temperature	472Â° F (USCG, 1999)
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	3.15 centistokes at 25 deg C
Solubility	greater than or equal to 100 mg/mL at 72Â° F (NTP, 1992)
Partition coefficient n-octanol/water	log Kow = 0.83
Vapour pressure	0.76 mm Hg at 68Â° F ; 0.88 mm Hg at 77Â° F; 300 mm Hg at 284Â° F (NTP, 1992)
Density and/or relative density	0.902 at 68Â° F (USCG, 1999)
Relative vapour density	4.07 (NTP, 1992) (Relative to Air)
Particle characteristics	no data available

SECTION 10: Stability and reactivity

10.1 Reactivity

The substance can form explosive peroxides. Reacts with strong oxidants. This generates fire and explosion hazard.

10.2 Chemical stability

no data available

10.3 Possibility of hazardous reactions

Combustible liquid when exposed to hear or flame.ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. It is liable to form peroxides on exposure to air and light. It attacks some forms of plastics, rubber and coatings. (NTP, 1992).

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Forms explosive mixture with air. ... Violent reaction with strong caustics adn strong oxidizers. Attacks some coatings, plastics and rubber. Attacks metallic aluminum at high temperatures.

10.6 Hazardous decomposition products

When heated to decomposition it emits acrid smoke and irritating fumes.

SECTION 11: Toxicological information

Acute toxicity

Oral: LD50 Rat oral 470 mg/kg
Inhalation: LC50 Rat (male) inhalation 486 ppm/4 hr from table
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

WEIGHT-OF-EVIDENCE CHARACTERIZATION: No reliable human epidemiological studies are available that address the potential carcinogenicity of EGBE. ... NTP /the National Toxicology Program/ reported no evidence of carcinogenic activity in male F344/N rats, and equivocal evidence of carcinogenic activity in female F344/N rats on the basis of increased combined incidences of benign and malignant pheochromocytoma (mainly benign) of the adrenal medulla. They also reported some evidence of carcinogenic activity in male B6C3F1 mice on the basis of increased incidences of hemangiosarcoma of the liver, and some evidence of carcinoma (mainly papilloma). ... because of the uncertain relevance of these tumor increases to humans, the fact that EGBE is generally negative in genotoxic tests and the lack of human data to support the findings in rodents, the human carcinogenic potential of EGBE, in accordance with the recently proposed Guidelines for Carcinogen Risk Assessment, cannot be determined at this time, but suggestive evidence exists from rodent studies. Under existing EPA guidelines, EGBE is judged to be a possible human carcinogen, Group C. There are currently no human epidemiological studies addressing the potential carcinogenicity of EGBE.

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

SECTION 12: Ecological information

12.1 Toxicity

Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill); Conditions: static; Concentration: 1,490 mg/L for 96 hr
Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Conditions: static; Concentration: 1,720 mg/L for 24 hr
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: A number of aerobic biological screening studies, which utilized settled waste water, sewage, or activated sludge for inocula, indicate that ethylene glycol mono-n-butyl ether should biodegrade rapidly in the environment(1-4). Five and ten-day Theoretical BOD values were 73% (with acclimation)(1) and 74%(2). The maximum Theoretical BOD reported was 88% for 20 days(2).

12.3 Bioaccumulative potential

An estimated BCF of 3 was calculated for ethylene glycol mono-n-butyl ether(SRC), using an estimated log Kow of 0.83(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low (SRC).

12.4 Mobility in soil

The Koc of ethylene glycol mono-n-butyl ether is estimated as 8(SRC), using a log Kow of 0.83(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that ethylene glycol mono-n-butyl ether is expected to have high mobility in soil.

12.5 Other adverse effects

no data available

SECTION 13: Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

SECTION 14: Transport information

14.1 UN Number

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

14.2 UN Proper Shipping Name

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

14.3 Transport hazard class(es)

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

14.4 Packing group, if applicable

ADR/RID: Not dangerous goods. (For reference only, please check.)

IMDG: Not dangerous goods. (For reference only, please check.)

IATA: Not dangerous goods. (For reference only, please check.)

14.5 Environmental hazards

ADR/RID: No

IMDG: No

IATA: No

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to IMO instruments

no data available

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-	Poly(oxy-1,2-ethanediyl), Î±-butyl-Ï-hydroxy-	9004-77-7	500-012-0
European Inventory of Existing Commercial Chemical Substances (EINECS)			Not Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Not Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.
Korea Existing Chemicals List (KECL)			Listed.

SECTION 16: Other information

Information on revision

Creation Date	July 15, 2019
Revision Date	July 15, 2019

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Polyethylene glycol monobutyl ether is included in Polyethylene Glycol Derivatives category.