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ENDOTHERM GmbH

Germany
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Company Profile

Serving as a contract research organization (CRO), Endotherm Life Science Molecules is a provider of medicinally relevant compounds for the discovery and development of novel small molecule drugs. The product range includes focused and diversified compound libraries, reference standards, building blocks and fluorescent probes for assay development.In cooperation CompChem Solutions, a molecular modelling provider, rational drug design efforts are supported by computer assisted tools towards the design of focused compound libraries for hit-finding, hit-to-lead studies and lead optimizations. Besides the support for projects in medicinal chemistry and exclusive synthesis of rare compounds for dedicated customers, approximately 2500 “inhouse-made” research chemicals can be selected from a continuously updated catalogue.Particularly, the company has established a technology platform for the synthesis of complex chiral natural products, such as Vitamin D derivatives, in turn to be used as compound libraries for screening, building blocks or for process research.Finally, Endotherm Life Science Molecules is involved with internal drug discovery programmes, such as EUTrigTreat, an EU funded integrated FP7 research project. The consortium has the aim to explore the genetic and environmental cause of arrhythmias and sudden cardiac death in order to develop new diagnostic tools and effective therapies. In collaboration with the Universit?t Heidelberg, new inhibitors of Mur-A, a target enzyme for the development of new antibiotics, are discovered.

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Product List

Product Name Synonyms CAS No. Grate/Content Operate

(2R,3R)-Diethyl 2,3-epoxysuccinate

DIETHYL (2R,3R)-(-)-2,3-EPOXYSUCCINATE;DIETHYL-(2R,3R)-2,3-EPOXYSUCCINATE;(2R,3R)-DIETHYL-2,3-EPOXY SUCCINATE;2,3-Oxiranedicarboxylicacid,diethylester,(2R,3R)-(9CI);diethyl (2R,3R)-oxirane-2,3-dicarboxylate;Oxirane-2,3-dicarboxylic acid diethyl ester;Diethyl (2R,3R)-(-)-2,3-epoxysuccinate,98%;trans-2,3-bis(ethoxycarbonyl)oxirane, (-)-(2R,3R)-trans-Oxiran-2,3-dicarbonsaeure-diethylester, diethyl (2R,3R)-(-)-oxirane-2,3-dicarboxylate, diethyl (2R,3R)-(-)-threo-2,3-epoxysuccinate, (2R,3R)-diethyl oxirane-2,3-dicarboxylate, diethyl (2R,3R)-oxirane-2,3-dicarboxylate, Diethyl (2R,3R)-threo-2,3-epoxysuccinate
74243-85-9 Inquiry

(S)-(+)-N-(2,3-Epoxypropyl)phthalimide

1H-Isoindole-1,3(2H)-dione,2-[(2S)-2-oxiranylmethyl]-;1H-Isoindole-1,3(2H)-dione,2-(oxiranylmethyl)-,(S)-;1H-Isoindole-1,3(2H)-dione,2-[(2S)-oxiranylmethyl]-;2-[(2S)-2-Oxiranylmethyl]-1H-isoindole-1,3(2H)-dione;N-((2S)-Oxiran-2-ylmethyl)phthalimide;2-[(S)-2-Oxiranylmethyl]-1H-isoindol-1,3(2H)-dione;N-(S)-Glycidylphthalimide;(S)-N-(2,3-Epoxypropan-1-yl)phthalimide;(S)-2-[(Oxiranyl)methyl]isoindole-1,3-dione;(S)-N-(2,3-Epoxypropyl)phthalimide;(S)-2-(Oxiran-2-ylmethyl)-1H-isoindole-1,3(2H)-dione;N-[(+)-Glycidyl]phthalimide;N-[(S)-(+)-Glycidyl]phthalimide;(S)-Glycidyl Phthalimide;(S)-N-Giycidylphthalimide;(S)-2-(Oxiran-2-ylmethyl)isoindoline-1,3-dione;(S)-N-Glycidylphthalimide;2-[[(2S)-Oxiran-2-yl]methyl]isoindole-1,3-dione
161596-47-0 Inquiry

1,2,3,4,6-O-Pentagalloylglucose

β-D-Glucopyranose,1,2,3,4,6-pentakis(3,4,5-trihydroxybenzoate);Glucopyranose,pentagallate,β-D-;β-D-Glucopyranose,pentakis(3,4,5-trihydroxybenzoate);Gallic acid,pentaester with β-D-glucopyranose;1,2,3,4,6-Pentagalloyl-β-D-glucose;Penta-O-galloyl-β-D-glucopyranose;Penta-O-galloyl-β-D-glucose;β-1,2,3,4,6-Pentagalloylglucose;1,2,3,4,6-Pentagalloyl-β-D-glucopyranose;1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose;1,2,3,4,6-Pentagalloyl-β-D-glucopyranoside;Pentagalloyl-D-glucose;Penta-O-galloylglucose;Gallotannin 15;1,2,3,4,6-Penta-O-galloyl-β-glucopyranose;1,2,3,4,6-Penta-O-galloyl-β-D-glucose;1,2,3,4,6-Penta-O-galloylglucose;1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranoside;1,2,3,4,6-Penta-O-galloyl-β-D-glucoside;G 7548;DB 03208;94008-28-3;98731-29-4;99935-72-5;102694-50-8;131647-34-2;1809258-59-0;2392017-59-1
14937-32-7 Inquiry

1,2-Benzenediol, 3-methoxy-6-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-

1,2-Benzenediol,3-methoxy-6-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-;1,2-Benzenediol,3-methoxy-6-[2-(3,4,5-trimethoxyphenyl)ethenyl]-,(Z)-;3-Methoxy-6-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-1,2-benzenediol;Combretastatin A1;OXi 4500
109971-63-3 Inquiry

1,3-Dioxolane,2-(2-bromoethyl)-2-methyl-

2-(2-bromoethyl)-2-methyl-1,3-dioxolane;1,3-Dioxolane, 2-(2-bromoethyl)-2-methyl-;ACMC-1AFVO;2-(2-Bromo-ethyl)-2-methyl-[1,3]dioxolane;SCHEMBL499476;CTK4H8923;DTXSID30473102;4-Bromo-2-butanone ethylene ketal;ZINC2556774;ANW-28745
37865-96-6 Inquiry

1,3-Dioxolane,2-(4-bromophenyl)-

RARECHEM AL BP 0075;2-(4-BROMOPHENYL)-1,3-DIOXOLANE;2-(P-BROMOPHENYL)-1,3-DIOXOLANE;1-BROMO-4-(1,3-DIOXOLAN-2-YL)BENZENE;4-BROMOBENZALDEHYDE ETHYLENE ACETAL;4-Bromophenyldioxolane;bromophenyldioxolane;2-(4-BROMOPHENYL)-1,3-DIOXOLANE 98+%
10602-01-4 Inquiry

2',3'-Dimethylacetophenone

2,3-DIMETHYLACETOPHENONE;2,3-DiMethylphenylethanone;1-(2,3-Dimethylphenyl)ethanone;ETHANONE,1-(2,3-DIMETHYLPHENYL);1-(2,3-dimethylphenyl)ethan-1-one;2,3-Dimethylacetophenone(MedetomidineIntermediate)
2142-71-4 Inquiry

2,4-Diaminopyrimidine-5-carboxaldehyde

2,4-DIAMINO-PYRIMIDINE-5-CARBALDEHYDE;2,4-DIAMINOPYRIMIDINE-5-CARBOXALDEHYDE;AURORA KA-6757;5-Pyrimidinecarboxaldehyde, 2,4-diamino- (6CI,8CI,9CI);2,4-Diamino-5-formylpyrimidine;2,4-DiaMino-5-pyriMidinecarboxaldehyde;2,6-DiaMino-5-pyriMidinecarboxaldehyde;NSC 211353
20781-06-0 Inquiry

2,6-Pyridinedicarboxaldehyde

2,6-Pyridinedicarboxaldehyde;2,6-Diformylpyridine;Pyridine-2,6-dicarbaldehyde;2,6-Pyridinedialdehyde;NSC 13393;2,6-Bis(formyl)pyridine
5431-44-7 Inquiry

2-Amino-6-chloro-3-nitropyridine

2-Pyridinamine,6-chloro-3-nitro-;Pyridine,2-amino-6-chloro-3-nitro-;6-Chloro-3-nitro-2-pyridinamine;2-Amino-6-chloro-3-nitropyridine;6-Amino-2-chloro-5-nitropyridine;6-Chloro-3-nitro-2-pyridylamine;6-Chloro-3-nitropyridin-2-ylamine;2-Amino-3-nitro-6-chloropyridine
27048-04-0 Inquiry

2-Azetidinecarboxylicacid, 1-[(1,1-dimethylethyl)dimethylsilyl]-4-oxo-, (2S)-

(4S)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-CARBOXYLIC ACID;(4S)-N-(TERT-BUTYLDIMETHYLSILYL)AZETIDIN-2-ONE-4-CARBOXYLIC ACID;(4S)-N-(tert-Butyldimethylsilyl)azetidin-2-one-2-caroxylic acid.;1-(tert-Butyl-dimethyl-silanyl)-4-oxo-azetidine-2-carboxylic acid;(4S)-N-(tert-Butyldimethylsilyl)azetidin-2-one-4-carboxylic acid,99%;2-Azetidinecarboxylicacid, 1-[(1,1-dimethylethyl)dimethylsilyl]-4-oxo-, (2S)-
82938-50-9 Inquiry

2-[(3,4-Dichlorophenyl)methylamino]ethanol

Ethanol,2-[[(3,4-dichlorophenyl)methyl]amino]-;Ethanol,2-(3,4-dichlorobenzylamino)-;2-[[(3,4-Dichlorophenyl)methyl]amino]ethanol;N-(3,4-Dichlorobenzyl)ethanolamine;NSC 91875;2-(3,4-Dichlorobenzylamino)ethanol;2-(3,4-Dichlorbenzylamino)ethanol;2-[[(3,4-Dichlorophenyl)methyl]amino]ethan-1-ol
40172-06-3 Inquiry

3-Amino-5-bromopyridine

3-amino-5-bronopyridine;3-AMINO-5-BOROMOPYRIDINE;5-bromopyridin-3-amine(SALTDATA: FREE);3-AMino-5-broMopyridi;5--3- aMinopyridinebroMide;3--5- aMinopyridinebroMide;13535-01-8;3-Amino-5-bromopyridine 97%
13535-01-8 Inquiry

4-Cyanobenzamide

Benzamide,4-cyano-;Benzamide,p-cyano-;4-Cyanobenzamide;p-Cyanobenzamide;4-Carbamoylbenzonitrile
3034-34-2 Inquiry

5-Formylthiophene-2-carboxylic acid

AKOSMSC-0225;AURORAKA-6755;5-FORMYLTHENOICACID;5-FORMYL-2-THIOPHENECARBOXYLICACID;5-FORMYL-THIOPHEN-2-CARBOXYLICACID;5-FORMYL-THIOPHENE-2-CARBOXYLICACID;5-Formyl-2-thiophenecarboxylicacid,98%;5-ForMyl-thiophene-2-carboxylicacidaMide;5-Carboxythiophene-2-carboxaldehyde,2-Carboxy-5-formylthiophene,5-Formyl-2-thenoicacid
4565-31-5 Inquiry

Acridine-9-carboxylic acid hydrate

NSC 386 Hydrate;9-Acridinecarboxylic acid hydrate 97%;TIMTEC-BB SBB000808;9-ACRIDINECARBOXYLIC ACID HYDRATE;9-ACRIDINECARBOXYLIC ACID MONOHYDRATE;ACRIDINE-9-CARBOXYLIC ACID HYDRATE
332927-03-4 Inquiry

Benzenebutanoic acid, b-amino-, 1,1-dimethylethyl ester,(bR)-

Benzenebutanoic acid,β-amino-,1,1-dimethylethyl ester,(βR)-;Benzenebutanoic acid,β-amino-,1,1-dimethylethyl ester,(R)-;1,1-Dimethylethyl (βR)-β-aminobenzenebutanoate;(3R)-3-Amino-4-phenylbutanoic acid tert-butyl ester;1,1-Dimethylethyl (3R)-3-amino-4-phenylbutanoate
166023-31-0 Inquiry

Boc-O-Benzyl-D-threoninol

Boc-D-Threoninol(Bzl);tert-butyl (2S,3S)-3-(benzyloxy)-1-hydroxybutan-2-ylcarbamate;(2S,3S)-2-(Boc-aMino)-3-benzyloxy-1-butanol, 97%;tert-butyl N-[(1S,2S)-2-Benzyloxy-1-(hydroxymethyl)propyl]carbamate;(2-BENZYLOXY-1-HYDROXYMETHYL-PROPYL)-CARBAMIDSAURE-TERT-BUTYL ESTER;N-tert-Butoxycarbonyl-(2S,3S)-2-amino-3-phenylmethoxy-1-butanol;N-BOC-D-THR(BZL)-OL-N-BOC-(2S,3S)-2-AMINO-3-BENZYLOXY-1-BUTANOL;N-alpha-t-Butyloxycarbonyl-O-benzyl-D-threoninol
168034-31-9 Inquiry

Calcitriol

1,3-Cyclohexanediol,4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-,(1R,3S,5Z)-;9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol,(1α,3β,5Z,7E)-;(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol;1,25-Dihydroxycholecalciferol;1α,25-Dihydroxycholecalciferol;1α,25-Dihydroxyvitamin D3;1,25-Dihydroxyvitamin D3;Calcitriol;1,25-Dihydroxyvitamin D;Ro 21-5535;Soltriol;Calcijex;Rocaltrol;1α,25-(OH)2D3;Topitriol;Silkis;Toptriol;Dihydroxyvitamin D3;(3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol;Panbonis;Solbone P;DN 101;1α,25-Hydroxyl-vitamin D3;1a,25-Dihydroxyvitamin D3;125338-24-1;69878-52-0;1000873-74-4
32222-06-3 Inquiry

Coenzyme A,S-butanoate, trilithium salt (9CI)

N-BUTYRYL COENZYME A LITHIUM SALT;BUTYRYL COENZYME A;BUTYRYL COENZYME A DILITHIUM SALT;C4:0;butyryl coenzyme a lithium salt hydrate;Butyryl coenzyme A lithium salt;Butyryl-Coenzym A Dilithiumsalz;coenzyme A n-butyryl derivative (C4:0), lithium salt
102282-28-0 Inquiry
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