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Histiocytic panniculitis
In 1980, Winklemann et al. first proposed the name of histiocytic phagocytic panniculitis and reported 5 cases. It is a benign histiocytic proliferative disease characterized by multiple tender subcutaneous nodules, high fever, hepatosplenomegaly, pancytopenia, bleeding, and abnormal blood coagulation. The main pathological feature is that histiocytes phagocytose blood components to form "bean bag" cells. This disease is caused by histiocytes with phagocytic activity infiltrating subcutaneous fat tissue. It often involves multiple organs, with subcutaneous nodules, fever, pancytopenia, bleeding, liver and kidney failure, etc.
  • Site of disease:

    skin
  • Infectious :

    Not contagious
  • Frequent population:

    All groups
  • Related symptoms:

    Subcutaneous nodules Lymph node enlargement Hepatomegaly Leukocytosis Nodules
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