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Idiopathic thrombocytopenia
Idiopathic thrombocytopenic purpura (ITP) refers to thrombocytopenia caused by no obvious exogenous cause, but most of the time it is caused by increased platelet destruction caused by immune response, so it is also called autoimmune thrombocytopenia. It is a common type of hemorrhagic blood disease, characterized by shortened platelet lifespan, increased bone marrow megakaryocytes, IgG antibodies in serum or platelet surface in 80%-90% of cases, and no obvious enlargement of the spleen. According to the pathogenesis, inducing factors and course of disease, ITP is divided into acute and chronic types. 80% of children are acute type (AITP), with no gender difference. It is easy to get sick in spring and winter. Once the source of the disease is cleared, the disease will be cured in June-December. More than 95% of adult ITP are chronic type (CITP), with a male to female ratio of about 1:3. It is generally considered to be an autoimmune disease that is difficult to cure. The mortality rate of this disease is about 1%, and most deaths are caused by intracranial hemorrhage. The main clinical manifestations of ITP are bleeding in the skin and mucous membranes or internal organs.
  • Site of disease:

    Skin blood vessels
  • Infectious :

    Not contagious
  • Frequent population:

    The acute type is more common in children under 10 years old. The chronic type...
  • Related symptoms:

    Purpura of skin and mucous membranes Negative urine bilirubin Fear of cold Easily bruises after collision Heavy menstrual flow
  • Concurrent disease:

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Indication: It is suitable for the prevention and treatment of various bleeding caused by hyperfibrinolysis. ⑴ Bleeding caused by trauma or surgery in organs rich in plasminogen activators such as the prostate, urethra, lungs, liver, pancreas, brain, uterus, adrenal glands, thyroid glands, and bleeding caused by excessive tissue plasminogen activator (t-PA), streptokinase or urokinase. ⑵ Late stage of disseminated intravascular coagulation (DIC) to prevent secondary hyperfibrinolysis. ⑶ It can be used as an auxiliary treatment for bleeding after tooth extraction or oral surgery or menorrhagia in hemophilia patients. ⑷ It can be used for symptomatic treatment of various bleeding such as upper gastrointestinal bleeding, hemoptysis, idiopathic thrombocytopenic purpura and leukemia. It has a significant effect on general chronic oozing; it has poor efficacy on bleeding caused by abnormal coagulation function; it is effective for severe bleeding, heavy bleeding from wounds and bleeding from cancer, etc.
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