Omsk hemorrhagic fever is an acute febrile disease. The virus has neurotropic characteristics and can produce lesions in various types of cell culture, such as Hela cells, chicken embryo cells, hamster kidney cells and monkey kidney cells. Its characteristics are: viral antigens, natural epidemic source, hemorrhagic symptoms and benign course. The patient suddenly develops fever, headache, back and limb pain, vomiting and diarrhea, pseudomeningitis, palate mucosal rash. The disease was discovered in 1941-1943 and was first reported in the northern rural areas of Omsk in Siberia, the former Soviet Union, from 1944 to 1945. There were two outbreaks of Omsk hemorrhagic fever in 1945 and 1946, with more than 200 and 600 people respectively.