Juvenile rheumatoid arthritis (JRA) is a common connective tissue disease in children, characterized by chronic arthritis and multiple systemic involvement, including joints, skin, muscles, liver, spleen, and lymph nodes. Younger children often have persistent irregular fever first, and their systemic symptoms are more significant than joint symptoms. Older children or adult patients are more limited to joint symptoms. The clinical manifestations of this disease vary greatly and can be divided into different types, so there are many names. Such as Still's disease (1897), juvenile rheumatoid recurrent fever type (Wissler Fanconi syndrome), juvenile chronic arthritis (juvenile chronic arthritis, JCA), juvenile rheumatoid disease (juvenile rheumatoid disease) and juvenile arthritis (juvenile arthritis, JA).