Broad-spectrum penicillin antibiotics, which can be hydrolyzed by β-lactamase. When used in combination with potassium clavulanate, its antibacterial spectrum is expanded, and it has good effects on enzyme-producing Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci and enterococci. It also has good antibacterial activity against certain β-lactamase-producing Enterobacteriaceae, Haemophilus influenzae, Moraxella catarrhalis, Bacteroides fragilis, etc.

It has only weak antibacterial activity itself, but has a strong broad-spectrum β-lactamase inhibitory effect, which can protect amoxicillin from β-lactamase hydrolysis.

Amoxicillin is a broad-spectrum penicillin antibiotic, which can protect it from hydrolysis by β-lactamase when used in combination with potassium clavulanate. It has good effects on enzyme-producing Staphylococcus aureus, Staphylococcus epidermidis, coagulase-negative Staphylococci and enterococci, and also has good antibacterial activity against certain β-lactamase-producing Enterobacteriaceae, Haemophilus influenzae, Moraxella catarrhalis, Bacteroides fragilis, etc.

Potassium clavulanate itself has only weak antibacterial activity, but has a strong broad-spectrum β-lactamase inhibitory effect, which can protect amoxicillin from β-lactamase hydrolysis. It has no effect on methicillin-resistant Staphylococcus aureus and Enterobacter, Enterobacteriaceae bacteria and Pseudomonas that produce chromosome-mediated type I enzymes.

Ticarcillin is a broad-spectrum bactericidal agent of the penicillin class. When combined with clavulanic acid, it becomes an antibiotic with broad-spectrum bactericidal effect and is suitable for the empirical treatment of a wide range of bacterial infectious diseases.

Clavulanic acid is an irreversible and highly effective β-lactamase inhibitor. It has little antibacterial effect alone, but it can restore ticarcillin sensitivity by blocking β-lactamase and enhance the antibacterial effect of ticarcillin.

Ticarcillin is a broad-spectrum penicillin-type bactericide that exerts its antibacterial effect by destroying bacterial cell wall synthesis. Clavulanic acid enhances its stability against β-lactamase and expands its antibacterial spectrum.

Clavulanic acid is an irreversible and highly effective β-lactamase inhibitor. It has little antibacterial effect alone, but it can restore its sensitivity and enhance the antibacterial effect when combined with ticarcillin.