Shenzhen Salubris Pharmaceuticals Co., Ltd.

Cefepime is a broad-spectrum fourth-generation cephalosporin that achieves bactericidal effects by inhibiting the biosynthesis of bacterial cell walls. It is effective against both gram-positive and gram-negative bacteria, is highly resistant to hydrolysis by most beta-lactamases, and can quickly penetrate into the cells of gram-negative bacteria. Its target molecule is penicillin-binding protein (PBP). In vitro and clinical studies have confirmed that this product is active against most of the following microorganisms: gram-negative aerobic microorganisms: Enterobacter, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa; gram-positive aerobic microorganisms: Staphylococcus aureus (only for methicillin-sensitive strains), Streptococcus pyogenes (Group A streptococci), Streptococcus pneumoniae.

Cefepime is a broad-spectrum fourth-generation cephalosporin that achieves bactericidal effects by inhibiting the biosynthesis of bacterial cell walls. It is effective against both gram-positive and gram-negative bacteria, is highly resistant to hydrolysis by most β-lactamases, and can quickly penetrate into the cells of gram-negative bacteria. Its target molecule is penicillin-binding protein (PBP). In vitro and clinical studies have confirmed that this product is active against a variety of microorganisms, including Enterobacter, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus (only for methicillin-sensitive strains), Streptococcus pyogenes (Group A Streptococcus), Streptococcus pneumoniae, etc.

Cefepime is a broad-spectrum fourth-generation cephalosporin that achieves bactericidal effects by inhibiting the biosynthesis of bacterial cell walls. In vitro tests have shown that this product is effective against both Gram-positive and Gram-negative bacteria. This product has low affinity for beta-lactamase encoded by bacterial chromosomes, is highly resistant to hydrolysis by most beta-lactamases, and can quickly penetrate into the cells of Gram-negative bacteria. In bacterial cells, its target molecule is penicillin-binding protein (PBP).

No specific pharmacological effects mentioned

This product is a first-generation cephalosporin, which has good antibacterial effect on some strains of Gram-positive cocci such as non-penicillinase-producing and penicillinase-producing Staphylococcus aureus, coagulase-negative Staphylococci, group A hemolytic streptococci, Streptococcus pneumoniae and viridans streptococci. Anaerobic Gram-positive bacteria are mostly sensitive to this product, while Bacteroides fragilis is resistant to it. Methicillin-resistant Staphylococci and Enterococci are resistant to this product. The effect of this product on Gram-positive and Gram-negative bacteria is similar to that of cephalexin. This product has a certain effect on gonococci and is also active against enzyme-producing gonococci; its activity against Haemophilus influenzae is poor.