Chengdu Beite Denuo Pharmaceutical Co., Ltd.
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Founded in:
2018-01-30 -
Country:
China -
Address:
No. 66, Kelin Road West Section, Chengdu Cross-Strait Science and Technology Industrial Development Park, Wenjiang District, Chengdu -
Tax NO.:
91510115MA6CA1BY4U -
Registered Funds:
182.776863 yuan -
Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Hydroxyl camptothecine |
Cell cycle specific drugs mainly act on the S phase and selectively inhibit DNA topoisomerase I (TOPOI). By inhibiting the activity of TOPOI, it blocks DNA replication and transcription, interfering with the proliferation cycle of tumor cells. It may also induce tumor cell differentiation and apoptosis.
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Cell cycle specific drugs mainly act on the S phase and selectively inhibit DNA topoisomerase I (TOPOI). By inhibiting the activity of TOPOI, it blocks DNA replication and transcription, interfering with the proliferation cycle of tumor cells. It may also induce tumor cell differentiation and apoptosis. |
0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Etoposide |
This product is a cell cycle-specific anti-tumor drug that acts on DNA topoisomerase II to form a stable reversible complex of drug-enzyme-DNA, which hinders DNA repair. Experiments have found that this complex can be reversed with the elimination of the drug, allowing the damaged DNA to be repaired and reducing cytotoxicity. Therefore, extending the drug administration time may increase the anti-tumor activity.
More
This product is a cell cycle-specific anti-tumor drug that acts on DNA topoisomerase II to form a stable reversible complex of drug-enzyme-DNA, which hinders DNA repair. Experiments have found that this complex can be reversed with the elimination of the drug, allowing the damaged DNA to be repaired and reducing cytotoxicity. Therefore, extending the drug administration time may increase the anti-tumor activity. |
33419-42-0 | 21 |