HE BEI YI PIN Pharmaceutical Co., Ltd.
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Founded in:
2013-05-29 -
Country:
China -
Address:
Sanxia Road, Shijiazhuang Economic and Technological Development Zone -
Tax NO.:
911300000694342458 -
Registered Funds:
68.68 million yuan -
Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Urapidil hydrochloride |
Urapidil is a benzoxazosin-substituted uracil, which has both peripheral and central hypotensive effects. Peripherally, it mainly blocks postsynaptic α1 receptors, causing vasodilation and significantly reducing peripheral resistance, while also having a weak presynaptic α2 blocking effect; the central effect is mainly through stimulating serotonin-1A (5-HT1a) receptors, reducing sympathetic feedback regulation of the medullary cardiovascular center and lowering blood pressure. While lowering blood pressure, it generally does not cause reflex tachycardia.
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Urapidil is a benzoxazosin-substituted uracil, which has both peripheral and central hypotensive effects. Peripherally, it mainly blocks postsynaptic α1 receptors, causing vasodilation and significantly reducing peripheral resistance, while also having a weak presynaptic α2 blocking effect; the central effect is mainly through stimulating serotonin-1A (5-HT1a) receptors, reducing sympathetic feedback regulation of the medullary cardiovascular center and lowering blood pressure. While lowering blood pressure, it generally does not cause reflex tachycardia. |
64887-14-5 | 21 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Urapidil hydrochloride |
Urapidil is a benzoxazosin-substituted uracil, which has both peripheral and central hypotensive effects. The periphery mainly blocks postsynaptic α1 receptors, causing vasodilation and significantly reducing peripheral resistance. It also has a weak presynaptic α2 blocking effect, blocking the vasoconstriction effect of catecholamines; the central effect is mainly through stimulating serotonin-1A (5-HT1a) receptors, reducing sympathetic feedback regulation of the medullary cardiovascular center and lowering blood pressure. While lowering blood pressure, it generally does not cause reflex tachycardia. In clinical open studies, single anesthesia can reduce systolic and diastolic blood pressure by 3.1% and 2.1%, respectively, and for hypertensive patients, it can reduce them by 12% and 6.7%, respectively.
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Urapidil is a benzoxazosin-substituted uracil, which has both peripheral and central hypotensive effects. The periphery mainly blocks postsynaptic α1 receptors, causing vasodilation and significantly reducing peripheral resistance. It also has a weak presynaptic α2 blocking effect, blocking the vasoconstriction effect of catecholamines; the central effect is mainly through stimulating serotonin-1A (5-HT1a) receptors, reducing sympathetic feedback regulation of the medullary cardiovascular center and lowering blood pressure. While lowering blood pressure, it generally does not cause reflex tachycardia. In clinical open studies, single anesthesia can reduce systolic and diastolic blood pressure by 3.1% and 2.1%, respectively, and for hypertensive patients, it can reduce them by 12% and 6.7%, respectively. |
64887-14-5 | 21 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Sevoflurane |
For inhalation
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For inhalation |
28523-86-6 | 13 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| OLPRINONE HYDROCHLORIDE |
Extract from the above information
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Extract from the above information |
119615-63-3 | 4 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Enflurane |
Extract from the above information
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Extract from the above information |
13838-16-9 | 3 |