Shanxi Shanyi Pharmaceutical Co., Ltd.

As a histamine H1 receptor antagonist, this product can counteract the capillary dilation caused by allergic reactions, reduce the permeability of capillaries, and relieve wheezing caused by bronchial smooth muscle contraction. This product has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics. This product is mainly metabolized in the liver.

One of the ingredients of the Chinese medicine bezoar, as an endogenous amino acid, is a central inhibitory transmitter that can regulate the excitability of nerve tissue and body temperature, so it has antipyretic, sedative, analgesic, anti-inflammatory, anti-rheumatic, anticonvulsant and other effects. In addition, it can improve the body's nonspecific immune function.

①Analgesic effect: It is mainly through inhibiting the synthesis of prostaglandins and other substances that can make pain sensitive to mechanical or chemical stimulation (such as bradykinin, histamine), and it is a peripheral analgesic. However, the possibility of central analgesia (possibly acting on the hypothalamus) cannot be ruled out; ②Anti-inflammatory effect: The exact mechanism is still unclear. It may be due to the fact that this product acts on inflamed tissues and inhibits the synthesis of prostaglandins or other substances that can cause inflammatory reactions (such as histamine) to play an anti-inflammatory role. Inhibition of the release of lysosomal enzymes and leukocyte chemotaxis may also be related to it; ③Antipyretic effect: It may act on the hypothalamic thermoregulatory center to cause peripheral vasodilation, increased skin blood flow, sweating, and increased heat dissipation to play an antipyretic role. This central effect may be related to the inhibition of prostaglandin synthesis in the hypothalamus; ④Anti-rheumatic effect: The anti-rheumatic mechanism of this product, in addition to antipyretic and analgesic effects, is mainly anti-inflammatory; ⑤Inhibition of platelet aggregation: It works by inhibiting platelet cyclooxygenase and reducing the production of prostaglandins.

A selective β2 receptor agonist, it can selectively stimulate the β2 receptors of bronchial smooth muscle and has a strong bronchodilator effect. Its aerosol inhalation has less stimulating effect on the heart than isoproterenol.

This product is a glucocorticoid drug with strong local anti-inflammatory and anti-allergic effects.