Zhejiang Ruixin Pharmaceutical Co., Ltd.

This product is the levorotatory form of tetramisole, which can selectively inhibit succinate dehydrogenase in the muscles of the worm, so that fumaric acid cannot be reduced to succinic acid, thereby affecting the anaerobic metabolism of the muscles of the worm and reducing energy production. When the worm comes into contact with it, it can depolarize the nerves and muscles, and the muscles will continue to contract and cause paralysis; the drug's cholinergic effect is conducive to the excretion of the worm. Its activity is about 1 to 2 times that of tetramisole (racemic form), but its toxic side effects are lower. In addition, the drug may have an inhibitory effect on the microtubule structure of the worm. Levamisole also has immune regulation and immune preparation functions.

It inhibits the activity of smooth muscles and glands innervated by postganglionic cholinergic nerves, and can stimulate or inhibit the central nervous system depending on the dosage of this product. The detoxification system antagonizes the effects of cholinesterase inhibitors at the M cholinergic receptor site, such as increasing the secretion of mucous glands and salivary glands in the trachea and bronchial system, contracture of bronchial smooth muscles, and hyperactivity of autonomic ganglia after stimulation. In addition, atropine can excite or inhibit the central nervous system, with a certain dose dependence. The effect on the heart, intestines and bronchial smooth muscles is stronger and more lasting than other belladonna alkaloids.

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Extract from the above information

Extract from the above information