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Founded in:
2002-01-08 -
Country:
China -
Address:
Development Road, Tianning Industrial Zone, Liandu District, Lishui City, Zhejiang Province -
Tax NO.:
91330000735259021T -
Registered Funds:
50 million yuan -
Website:
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Email:
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea |
This product is a non-specific drug for the cell cycle. It is most sensitive to cells at the G1-S boundary or early S phase, and also has an inhibitory effect on the G2 phase. After entering the body, its molecule breaks into two parts from the carbamide bond. One part is the chloroethylamine part, which dissociates chlorine to form ethylene carbon cations, exerts a hydrocarbonization effect, breaks the DNA chain, and RNA and proteins are hydrocarbonized, which is related to the anti-tumor effect; the other part is the carbamoyl part that becomes isocyanate, or is converted into carbamic acid to exert a carbamylation effect, which mainly reacts with proteins, especially the amino group at the end of lysine, which is mainly related to bone marrow toxicity. Carbamylation also destroys some enzyme proteins, making it difficult to repair DNA after damage, which helps the anti-cancer effect. This product has no cross-resistance with other alkylating agents.
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This product is a non-specific drug for the cell cycle. It is most sensitive to cells at the G1-S boundary or early S phase, and also has an inhibitory effect on the G2 phase. After entering the body, its molecule breaks into two parts from the carbamide bond. One part is the chloroethylamine part, which dissociates chlorine to form ethylene carbon cations, exerts a hydrocarbonization effect, breaks the DNA chain, and RNA and proteins are hydrocarbonized, which is related to the anti-tumor effect; the other part is the carbamoyl part that becomes isocyanate, or is converted into carbamic acid to exert a carbamylation effect, which mainly reacts with proteins, especially the amino group at the end of lysine, which is mainly related to bone marrow toxicity. Carbamylation also destroys some enzyme proteins, making it difficult to repair DNA after damage, which helps the anti-cancer effect. This product has no cross-resistance with other alkylating agents. |
0 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Dobutamine hydrochloride |
Unspecified
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Unspecified |
49745-95-1 | 36 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Dobutamine hydrochloride |
Extract from the above information
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Extract from the above information |
49745-95-1 | 36 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Mitoxantrone hydrochloride |
|
70476-82-3 | 17 |
| Name | Description | Content | CAS NO. | Registered Holders |
|---|---|---|---|---|
| Mitoxantrone hydrochloride |
By binding to DNA molecules, it inhibits nucleic acid synthesis and causes cell death. This product is a non-specific drug for the cell cycle. It has no complete cross-resistance with anthracycline drugs.
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By binding to DNA molecules, it inhibits nucleic acid synthesis and causes cell death. This product is a non-specific drug for the cell cycle. It has no complete cross-resistance with anthracycline drugs. |
70476-82-3 | 17 |