Aminoglycoside antibiotics have good antibacterial effects on Gram-negative and Gram-positive bacteria. Their mechanism of action is to bind to the 30S subunit of bacterial ribosomes and inhibit bacterial protein synthesis. In recent years, the number of Gram-negative bacteria resistant to gentamicin has increased significantly.

Can relieve gastrointestinal smooth muscle spasm and inhibit glandular secretion

Azithromycin is a 15-membered macrolide antibiotic that has antibacterial effects on a variety of Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, anaerobic bacteria, sexually transmitted disease microorganisms and other microorganisms. It mainly binds to the 50S subunit of the bacterial ribosome and inhibits RNA-dependent protein synthesis.

Extract from the above information

As a histamine H1 receptor antagonist, it can counteract capillary dilation caused by allergic reactions, reduce capillary permeability, relieve wheezing caused by bronchial smooth muscle contraction, has a long-lasting antihistamine effect and obvious central nervous system inhibitory effect, and can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics. It is mainly metabolized in the liver.