It achieves bactericidal effect by inhibiting the synthesis of bacterial cell wall. It has bactericidal effect on a wide range of common clinical bacteria and can resist hydrolysis by multiple beta-lactamases. Bacteria sensitive to this product include Gram-positive bacteria and Gram-negative bacteria, as well as some anaerobic bacteria.

It achieves bactericidal effect by inhibiting the synthesis of bacterial cell wall. It has bactericidal effect on a wide range of common clinical bacteria and can resist hydrolysis by multiple beta-lactamases. Bacteria sensitive to this product include Gram-positive bacteria: Staphylococcus aureus (including strains that produce and do not produce penicillinase), Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, and Streptococcus agalactiae. Gram-negative bacteria: Escherichia coli, Klebsiella, Enterobacter, Citrobacter, Haemophilus influenzae (including strains that produce and do not produce beta-lactamase), Proteus mirabilis, Proteus vulgaris, Morganella morganii, Providencia, Serratia, Salmonella, Shigella. Pseudomonas aeruginosa and some other Pseudomonas, some strains of calcoacetic Acinetobacter. Neisseria gonorrhoeae (including strains that produce and do not produce penicillinase), Neisseria meningitidis, Bordetella pertussis. Anaerobic bacteria: Peptococcus, Peptostreptococcus, Veillonella, Clostridium, Eubacterium, Lactobacillus, Fusobacterium, various strains of Bacillus fragilis, and other Bacteroides.

This product is a third-generation cephalosporin antibiotic. It has high antibacterial activity against Escherichia coli, Klebsiella pneumoniae and other Enterobacteriaceae, Haemophilus influenzae, Pseudomonas aeruginosa, etc. It also has good antibacterial effects on nitrate-negative bacilli, Alcaligenes, etc. Most beta-lactamases produced by bacteria are highly stable, so it can still have antibacterial activity against multi-drug resistant strains of most of the above-mentioned Gram-negative bacilli. Gram-positive cocci such as pneumococci and hemolytic streptococci are highly sensitive to this product, but this product has only moderate activity against staphylococci, while enterococci and methicillin-resistant Staphylococci are often resistant to this product. This product has certain antibacterial activity against anaerobic bacteria such as Peptococcus and Peptostreptococci, but has poor antibacterial effect against Bacteroides fragilis. Its mechanism of action is to bind to penicillin-binding proteins (PBPs) on the bacterial cell membrane, acylate the transpeptidase, inhibit the synthesis of the bacterial septum and cell wall, affect the cross-linking of the cell wall mucopeptide components, inhibit cell division and growth, elongate the bacterial morphology, and finally dissolve and die.

This product is an antibiotic drug. Except for enterococci, methicillin-resistant and penicillin-resistant Staphylococcus aureus, it has good antibacterial activity against other Gram-positive cocci. Pneumococci and lytic streptococci are highly sensitive to this product. Diphtheria Corynebacterium, anthrax Bacillus, Listeria and Clostridium are sensitive to this drug. This product has stronger antibacterial activity against Escherichia coli, Proteus mirabilis and Klebsiella pneumoniae than cephalothin and cefotaxime, but its antibacterial effect against high-content bacteria is weaker than the latter two. Salmonella typhi and Shigella are sensitive to this drug, while other Enterobacteriaceae, Acinetobacter and Pseudomonas aeruginosa and Bacteroides fragilis are resistant. Neisseria is quite sensitive to this product, while influenza bacilli are only moderately sensitive.

Amoxicillin is a penicillin antibiotic that has good antibacterial activity against Streptococcus such as Streptococcus pneumoniae and hemolytic Streptococcus, aerobic Gram-positive cocci such as non-penicillinase-producing Staphylococci and Enterococcus faecalis, aerobic Gram-negative bacteria such as Escherichia coli, Proteus mirabilis, Salmonella, Haemophilus influenzae, Neisseria gonorrhoeae, and Helicobacter pylori. Amoxicillin exerts its bactericidal effect by inhibiting the synthesis of bacterial cell walls, which can quickly dissolve and rupture bacteria into spherical bodies.