Dopamine Capsules
Function and Efficacy
This product is a compound preparation, containing levodopa and benserazide. Benserazide is a peripheral decarboxylase inhibitor, which is not easy to enter the central nervous system. It only inhibits the conversion of peripheral levodopa into dopamine, increasing the content of levodopa in the circulation by 5-10 times, and thus the amount of levodopa entering the central nervous system also increases. Levodopa is converted into dopamine by dopa decarboxylase in the brain to exert its pharmacological effects and improve the symptoms of Parkinson's disease. The combination of benserazide and levodopa can not only reduce the adverse reactions of levodopa in the peripheral cardiovascular system, but also reduce the dosage of levodopa.
Ingredients
This product is a compound preparation, its components are: levodopa and benserazide hydrochloride.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| LevodopaIngredients |
It is converted into dopamine by dopa decarboxylase in the brain, improving the symptoms of Parkinson's disease More |
59-92-7 | 36 | |
| Benserazide hydrochlorideIngredients |
Peripheral decarboxylase inhibitors are not easy to enter the central nervous system, and only inhibit the conversion of peripheral levodopa into dopamine, thereby reducing the dosage of levodopa and its adverse reactions in the peripheral cardiovascular system. More |
14919-77-8 | 17 |
Indication
Used for Parkinson's disease and Parkinson's syndrome.
Usage and Dosage
Take orally 125 mg twice a day in the first week; increase by 125 mg every other week thereafter. Generally, the daily dose should not exceed 1 g, divided into 3 to 4 doses. The maintenance dose is 250 mg once, 3 times a day.
Adverse Reactions
The more common adverse reactions are nausea, vomiting, orthostatic hypotension, abnormal involuntary movements of the head, face, tongue, upper limbs and upper body, depression, and dysuria. Less common adverse reactions are hypertension, arrhythmia, and hemolytic anemia.
Precautions
It is contraindicated for patients with severe mental illness, severe arrhythmia, heart failure, glaucoma, peptic ulcer and a history of convulsions.
Drug Interactions
1. This product combined with non-selective monoamine oxidase inhibitors may cause acute adrenal crisis. 2. This product combined with papaverine or vitamin B6 may reduce the efficacy of this product. 3. This product combined with acetylspiramycin can significantly reduce the blood concentration of this product and weaken the efficacy. 4. This product combined with reserpine can inhibit the effect of this product and should be avoided. 5. This product combined with antipsychotic drugs should be avoided because the two antagonize each other. 6. This product combined with methyldopa can increase the adverse reactions of this product and enhance the antihypertensive effect of methyldopa.
Storage
Keep away from light, tightly closed, in a cool and dry place.
Packaging Specification
Levodopa 100 mg and benserazide 25 mg (equivalent to benserazide hydrochloride 28.5 mg)
Manufacturer
Guangzhou Baiyunshan Pharmaceutical Co., Ltd. Guangzhou Baiyunshan Pharmaceutical General
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Founded in:
1973-07-01 -
Address:
No. 88, Yunxiang Road, Tonghe Street, Baiyun District, Guangzhou -
Tax NO.:
91440101714253245D -
Registered Funds:
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Website:
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Email: