Nicergoline for injection

This product is a semi-synthetic ergot alkaloid derivative. It has alpha-receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It promotes the conversion of neurotransmitter dopamine to increase nerve conduction, strengthens the synthesis of brain protein, and improves brain function.

The chemical component is nicergoline. Its chemical name is: 10alpha;-methoxy-1,6-dimethylergoline-8beta;-methanol-5-bromo-3-pyridinecarboxylate. Its chemical structural formula is: Molecular formula: C24H26N3O3Br Molecular weight: 484.392.

This product is white or off-white freeze-dried loose mass or powder.

1. Improve low desire and emotional disorders (slow reaction, lack of concentration, memory loss, lack of ideas, depression, anxiety, etc.) caused by cerebral arteriosclerosis and sequelae of cerebral stroke. 2. Acute and chronic peripheral circulatory disorders (limb vascular occlusive disease, Raynaud's syndrome, other symptoms of poor peripheral circulation). It is also suitable for vascular dementia, especially in the early stage of treatment, it can improve cognition, memory, etc., and can reduce the severity of the disease.

Intramuscular injection: 2-4 mg each time, twice a day. Intravenous drip: 4-8 mg each time, dissolved in 100 ml of saline or glucose solution and slowly dripped, several times a day as specified by the doctor. Arterial injection: 4 mg each time, dissolved in 10 ml of saline, slowly injected over 2 minutes. Dosage: The treatment period and route of administration can be adjusted according to the clinical condition.

Flushing, tinnitus, dizziness, fatigue, low fever, mild gastrointestinal discomfort, and decreased blood pressure may be seen. Occasionally, frequent urination, oral fissures, and mild changes in liver and kidney function and total cholesterol may be seen.

This product is not suitable for the following situations: recent myocardial infarction, acute bleeding, severe bradycardia, orthostatic regulation dysfunction, bleeding tendency and allergy to nicergoline.

Nicergoline tablets may enhance the effects of antihypertensive drugs. Since nicergoline is metabolized by CYTP4502D6, interactions with drugs that are metabolized by the same pathway cannot be ruled out.

Keep away from light, tightly closed, in a cool place.

2mg

Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.

• Founded in:

  2000-09-29

• Address:

  No. 88 Tianxing Avenue, Qionglai City, Sichuan Province

• Tax NO.:

  915101832024104543

• Registered Funds:

  75 million yuan

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