Nicergoline for injection

This product is a semi-synthetic ergot alkaloid derivative. It has α-receptor blocking and vasodilation effects. It can enhance the metabolism of brain cell energy and increase the utilization of oxygen and glucose. It promotes the conversion of neurotransmitter dopamine to increase nerve conduction, strengthens the synthesis of brain protein, and improves brain function.

10α-Methoxy-1,6-dimethylergoline-8β-methylol-5-bromonicotinate

This product is white or off-white loose mass or powder.

1. Improve low desire and emotional disorders (slow reaction, lack of concentration, memory loss, lack of ideas, depression, anxiety, etc.) caused by cerebral arteriosclerosis and sequelae of cerebral stroke. 2. Acute and chronic peripheral circulatory disorders (limb vascular occlusive disease, Raynaud's syndrome, other symptoms of poor peripheral circulation). It is also suitable for vascular dementia, especially in the early stage of treatment, it can improve cognition, memory, etc., and can reduce the severity of the disease.

Intramuscular injection: 2-4 mg each time, twice a day. Intravenous drip: 4-8 mg each time, diluted with 100 ml of 0.9% sodium chloride injection or glucose injection, then intravenously dripped, 1-2 times a day. Arterial injection: 4 mg each time, diluted with 10 ml of 0.9% sodium chloride injection, then slowly injected (2 minutes).

No serious adverse reactions have been reported. There may be hypotension, dizziness, stomach pain, hot flashes, facial flushing, drowsiness, insomnia, etc. In clinical trials, an increase in uric acid concentration in the blood was observed, but this phenomenon was not related to the dosage and administration time.

This product is not suitable for the following situations: recent myocardial infarction, acute bleeding, severe bradycardia, orthostatic regulation dysfunction, bleeding tendency and allergy to nicergoline.

Nicergoline tablets may enhance the effects of antihypertensive drugs. Since nicergoline is metabolized by CYTP4502D6, interactions with drugs that are metabolized by the same pathway cannot be ruled out.

Keep in a dark, airtight container in a cool place. Valid for 18 months.

8mg

Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.

• Founded in:

  2000-09-29

• Address:

  No. 88 Tianxing Avenue, Qionglai City, Sichuan Province

• Tax NO.:

  915101832024104543

• Registered Funds:

  75 million yuan

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