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Isosorbide Mononitrate Sodium Chloride Injection

Ingredients

Ingredients: Injection: isosorbide mononitrate 20 mg, sodium chloride NaCl 2.25 g, chemical name: 1,4:3,6-dianhydro-D-sorbitol-5-mononitrate and sodium chloride.

Name Description Content CAS NO. Manufacturer
Isosorbide 5-mononitrateIngredients

16051-77-7 23
Sodium chlorideExcipients

7647-14-5 43

Appearance

The content of this product is colorless clear liquid.

Indication

Vasodilator. Suitable for the treatment of angina pectoris and congestive heart failure.

Usage and Dosage

Intravenous drip. The drug dosage can be adjusted according to the patient's response. The general effective dose is 2-7 mg per hour. The starting dose is 60 μg/min, and the general dose is 60-120 μg/min, once a day, 20 mg each time, and 10 days as a course of treatment.

Adverse Reactions

Like other nitrate drugs, during use, especially in the early stages of administration, symptoms such as headache and nausea may occur due to vasodilation. 1. Common symptoms include: dizziness, fainting, and flushing of the cheeks and neck caused by postural hypotension; in severe cases, persistent headaches, nausea, vomiting, tachycardia, and irritability may occur; rashes, blurred vision, and dry mouth are rare. 2. Clinical manifestations of overdose: In order of incidence, they are: bluish lips and nails, dizziness, head swelling, shortness of breath, extreme fatigue, fast and weak heartbeat, fever, and even convulsions.

Precautions

It is contraindicated in patients with glaucoma, anemia, head trauma, cerebral hemorrhage, severe hypotension or hypovolemia, and those who are sensitive to this product or nitrates.

Drug Interactions

Other vasodilators, especially alcohol, can increase the vasodilator effect of this product. It has been reported that the combination with calcium blockers causes obvious symptoms of postural hypotension, so the dosage should be reduced when used in combination.

Storage

Store at room temperature in a dark place and tightly sealed.

Packaging Specification

250ml: 20mg isosorbide mononitrate and 2.25g sodium chloride

Manufacturer

Cisen Pharmaceutical Co., Ltd.

  • Founded in:

    1998-11-06
  • Address:

    Tongji Science and Technology Industrial Park, Jining High-tech Zone
  • Tax NO.:

    91370800706117999P
  • Registered Funds:

    452,754,129 yuan
  • Website:

  • Email:

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