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Kanamycin Sulfate Eye Drops

Function and Efficacy

Kanamycin is an aminoglycoside antibiotic. It has a good effect on most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Proteus, Enterobacter, Shigella, Salmonella, Citrobacter, Providencia, Yersinia, etc.; influenza bacillus, Brucella, meningococcus, gonococci, etc. are also mostly sensitive to this product, and it is ineffective against Pseudomonas aeruginosa. It also has a certain effect on methicillin-sensitive strains of Staphylococcus and Mycobacterium tuberculosis. Other Gram-positive bacteria such as hemolytic streptococci, Streptococcus pneumoniae, enterococci and anaerobic bacteria are mostly resistant to this product. Kanamycin mainly binds to the 30S subunit of the bacterial ribosome and inhibits the synthesis of bacterial proteins. Kanamycin has complete cross-resistance with streptomycin and neomycin, and may have partial cross-resistance with other aminoglycosides.

Ingredients

Kanamycin Sulfate

Name Description Content CAS NO. Manufacturer
Kanamycin sulfateIngredients

Kanamycin is an aminoglycoside antibiotic. It has a good effect on most Enterobacteriaceae, such as Escherichia coli, Klebsiella, Proteus, Enterobacter, Shigella, Salmonella, Citrobacter, Providencia, Yersinia, etc.; influenza bacillus, Brucella, meningococcus, gonococci, etc. are also mostly sensitive to this product, and it is ineffective against Pseudomonas aeruginosa. It also has a certain effect on methicillin-sensitive strains of Staphylococcus and Mycobacterium tuberculosis. Other Gram-positive bacteria such as hemolytic streptococci, Streptococcus pneumoniae, enterococci and anaerobic bacteria are mostly resistant to this product. Kanamycin mainly binds to the 30S subunit of the bacterial ribosome and inhibits the synthesis of bacterial proteins. Kanamycin has complete cross-resistance with streptomycin and neomycin, and may have partial cross-resistance with other aminoglycosides.

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25389-94-0 9

Appearance

This product is a colorless or slightly yellow clear liquid.

Indication

It is suitable for the treatment of conjunctivitis, keratitis, dacryocystitis, blepharitis, tarbomitis and other infections caused by sensitive bacteria such as Escherichia coli, Klebsiella, Proteus, Neisseria gonorrhoeae and Staphylococcus.

Usage and Dosage

Instill into the conjunctival sac, 1 to 2 drops at a time, 3 to 5 times a day.

Adverse Reactions

Occasionally there may be mild eye irritation and discomfort, but no systemic adverse reactions.

Precautions

Patients who are allergic to this product or other aminoglycosides are contraindicated.

Drug Interactions

1. When used in combination with other aminoglycosides or applied topically successively, it may increase ototoxicity, nephrotoxicity and neuromuscular blocking effects. 2. When used in combination with capreomycin, cisplatin, ethacrynic acid, furosemide or vancomycin (or norvancomycin), or applied topically successively, it may increase ototoxicity and nephrotoxicity. 3. When used topically with cephalothin or cefazolin, it may increase nephrotoxicity. 4. Other nephrotoxic and ototoxic drugs should be used with caution when used in combination or applied successively with this product to avoid aggravating nephrotoxicity or ototoxicity.

Storage

Keep tightly closed in a cool, dark place.

Packaging Specification

8ml:40mg (calculated according to C18H36N4O11)

Manufacturer

Yunnan Phyto Pharmaceutical Co., Ltd.

  • Founded in:

    1998-10-26
  • Address:

    No. 2899, Macheng Road, Majinpu, High-tech Zone, Kunming City, Yunnan Province
  • Tax NO.:

    915300007097131980
  • Registered Funds:

    131.12 million yuan
  • Website:

  • Email:

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