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Artificial Bezoar Metronidazole Capsules

Ingredients

This product is a compound preparation, each tablet contains 200mg of metronidazole and 5mg of artificial bezoar. Excipients: starch.

Name Description Content CAS NO. Manufacturer
Atificial Cow-bezoarIngredients

1002-00-2 2

Appearance

This product is a capsule, and the contents are yellow or slightly yellow granules or powder.

Usage and Dosage

Oral administration: 2 capsules at a time, 3 times a day.

Adverse Reactions

1. The most serious adverse reactions of this product are epileptic seizures and peripheral neuropathy at high doses, the latter of which is mainly manifested as numbness and paresthesia of the extremities. In some cases, long-term use of the drug may cause persistent peripheral neuropathy. 2. Other common adverse reactions include: (1) Gastrointestinal reactions, such as nausea, loss of appetite, vomiting, diarrhea, abdominal discomfort, taste changes, dry mouth, metallic taste in the mouth, etc. (2) Reversible neutropenia. (3) Allergic reactions, rash, urticaria, itching, etc. (4) Central nervous system symptoms, such as headache, dizziness, syncope, paresthesia, limb numbness, ataxia and mental confusion, etc. (5) Others include fever, vaginal candidiasis, cystitis, difficulty urinating, dark urine color, etc., which are all reversible and will recover on their own after stopping the drug.

Precautions

1. Patients who are allergic to metronidazole or azole drugs are prohibited from using this product. 2. Patients with active central nervous system diseases and blood diseases are prohibited from using this product. 3. Pregnant women are prohibited from using this product. 4. People who drink alcohol are prohibited from using this product.

Special Population Medication

Precautions for children: Children should use it with caution and in reduced dosage. Precautions for pregnancy and lactation: Metronidazole can pass through the placenta and quickly enter the fetal circulation. Animal experiments have found that oral administration is non-toxic to the fetus. There is no sufficient and strict control observation of the effect of metronidazole on the fetus. Therefore, pregnant women are prohibited from using it. The concentration of metronidazole in breast milk is similar to that in blood. Animal experiments have shown that this product has a carcinogenic effect on young mice, so it is not suitable for lactating women. If the drug must be used, breastfeeding should be interrupted, and breastfeeding can be resumed 24 to 48 hours after the end of the treatment course. Precautions for the elderly: Due to decreased liver function in the elderly, the pharmacokinetics of this product are changed when it is used, and the blood drug concentration needs to be monitored.

Drug Interactions

1. Metronidazole can inhibit the metabolism of warfarin and other oral anticoagulants, enhance their effects, and cause a prolongation of the prothrombin time. 2. When used in combination with drugs that induce liver microsomal enzymes, such as phenytoin sodium and phenobarbital, the metabolism of this product can be enhanced, the blood concentration can be reduced, and the excretion of phenytoin sodium can be slowed down. 3. When used in combination with drugs that inhibit the activity of liver microsomal enzymes, such as cimetidine, the metabolism and excretion of this product in the liver can be slowed down, and the blood elimination half-life (t1/2β) of this product can be prolonged. The dosage should be adjusted according to the results of blood drug concentration determination. 4. This product can interfere with the metabolism of disulfiram. When the two are used together, patients may experience mental symptoms after drinking. Therefore, those who have used disulfiram within 2 weeks should not use this product again. 5. This product can interfere with the determination results of serum aminotransferase and lactate dehydrogenase

Storage

Keep in dark place and sealed

Packaging Specification

12 pieces

Validity Period

24 months

Manufacturer

Chenxin Pharmaceutical Jilin Co., Ltd.

  • Founded in:

    2006-12-29
  • Address:

    Shuangliao City Liaodong Economic Zone
  • Tax NO.:

    912203827593162460
  • Registered Funds:

    33 million yuan
  • Email:

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