Isosorbide mononitrate extended-release tablets
Function and Efficacy
Isosorbide mononitrate is the main active metabolite of isosorbide dinitrate. It can reduce myocardial oxygen consumption by dilating peripheral blood vessels, especially increasing venous blood volume, reducing reflux, and reducing cardiac preload and postload; it can also improve blood supply to ischemic areas by promoting myocardial blood flow redistribution, and may play an anti-myocardial ischemic role through these two aspects.
Ingredients
The main ingredient of this product is isosorbide mononitrate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Isosorbide 5-mononitrateIngredients |
It can reduce myocardial oxygen consumption by dilating peripheral blood vessels, especially increasing venous blood volume, reducing reflux, and lowering cardiac anterior and posterior loads; it can also improve blood supply to the ischemic area by promoting redistribution of myocardial blood flow, and may exert its anti-myocardial ischemia effect through these two aspects. More |
16051-77-7 | 22 |
Appearance
This product is an off-white tablet or film-coated tablet, which appears white or off-white after removing the coating.
Indication
Long-term treatment of coronary heart disease; prevention of angina pectoris; treatment of persistent angina pectoris after myocardial infarction; combined with digitalis and/or diuretics to treat chronic congestive heart failure.
Usage and Dosage
Oral: Take 1 tablet every morning. For severe cases, take 2 tablets every morning. If headache occurs, the initial dose can be reduced to half a tablet per day. The whole tablet or half tablet should be kept intact before taking, swallowed with half a cup of water, and should not be chewed or crushed.
Adverse Reactions
Nitrate-induced vasodilatory headache may occur in the early stage of medication, but the symptoms usually disappear after taking it for several days. Facial flushing, dizziness, orthostatic hypotension and reflex tachycardia may also occur. Occasionally, blood pressure is significantly reduced, bradycardia, angina pectoris is aggravated and syncope may occur.
Precautions
It is contraindicated for patients with glaucoma, shock, significant hypotension, hypertrophic obstructive heart disease, acute myocardial infarction, and severe cerebral arteriosclerosis.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use with caution in pregnant and lactating women. Precautions for the elderly: Not yet clear.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in sealed container.
Packaging Specification
40 mg
Validity Period
24 months.
Manufacturer
Shanghai New Asiatic Medicine Industry Minhang Co., Ltd.
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Founded in:
1989-07-06 -
Address:
No. 1500, Kunyang Road, Minhang District, Shanghai -
Tax NO.:
91310112133354160Q -
Registered Funds:
57.5 million yuan -
Email: