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Nifedipine extended-release tablets

Function and Efficacy

Nifedipine (NF) inhibits the influx of calcium ions into cells by blocking the membrane transport of calcium ions in myocardial and vascular smooth muscle, causing decreased myocardial contractility and vasodilation. Animal experiments have shown that by reducing myocardial contractility and peripheral vascular resistance, myocardial oxygen consumption is reduced; by dilating coronary vessels and developing collateral circulation, oxygen supply to myocardial ischemic sites is increased; by inhibiting the consumption of high-energy phosphate compounds, the ability to resist hypoxia is enhanced.

Ingredients

The main ingredient of this product is nifedipine.

Name Description Content CAS NO. Manufacturer
NifedipineIngredients

By blocking the membrane transport of calcium ions in myocardial and vascular smooth muscle, inhibiting the influx of calcium ions into cells, it causes a decrease in myocardial contractility and vasodilation. It reduces myocardial contractility and peripheral vascular resistance, thereby reducing myocardial oxygen consumption; by dilating coronary vessels and developing collateral circulation, it increases oxygen supply to myocardial ischemic areas; by inhibiting the consumption of high-energy phosphate compounds, it enhances the ability to resist hypoxia.

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Appearance

This product is a yellow film-coated tablet, which appears yellow after removing the coating.

Indication

Various types of hypertension and angina pectoris.

Usage and Dosage

Oral, once a day, the initial dose is 20 mg (1 tablet) each time. Depending on the condition and under the guidance of a doctor, it can be increased to 40-60 mg each time. This product cannot be chewed or broken when taken.

Adverse Reactions

1. Liver: Occasionally, jaundice and elevated glutamate oxaloacetate aminotransferase and glutamate pyruvate aminotransferase may occur. 2. Circulatory system: Occasionally, chest pain, headache, flushing, dizziness, palpitations, blood pressure drops below normal, lower limb edema may occur. 3. Allergies: Occasionally, allergic symptoms such as urticaria and itching may occur. 4. Digestive system: Occasionally, abdominal pain, nausea, loss of appetite, constipation may occur. 5. Oral cavity: Gum hypertrophy may occur. 6. Metabolic abnormalities: Occasionally, symptoms of hyperglycemia may occur.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: Children are prohibited from using. Precautions for pregnancy and lactation: Precautions for pregnant and lactating women are prohibited. Precautions for the elderly: See [Usage and Dosage] or follow the doctor's advice.

Drug Interactions

This experiment has not been conducted and there are no reliable references.

Storage

Keep away from light and store in sealed container.

Packaging Specification

20mg

Validity Period

Tentative 24 months

Manufacturer

Zhejiang Tailisen Pharmaceutical Co., Ltd.

  • Founded in:

    1995-12-29
  • Address:

    No. 200, Xinqiao North Road, Haiyan Economic Development Zone, Zhejiang Province
  • Tax NO.:

    913304242548470178
  • Registered Funds:

    15 million yuan
  • Website:

  • Email:

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