Niacin Tablets
Function and Efficacy
Nicotinic acid is converted into nicotinamide in the body, and then combined with riboadenin to form nicotinamide adenine dinucleotide (coenzyme I) and nicotinamide adenine dinucleotide phosphate (coenzyme II), which are necessary for lipid amino acid, protein, purine metabolism, tissue respiration oxidation and glycogenolysis. Nicotinic acid can reduce the utilization of coenzyme A; by inhibiting the synthesis of very low density lipoprotein (VLDL), it affects the transport of cholesterol in the blood. Large doses can reduce serum cholesterol and triglyceride concentrations. Nicotinic acid has a peripheral vasodilation effect.
Ingredients
The main ingredient of this product is: niacin.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Nicotinic acidIngredients |
Nicotinic acid is converted into nicotinamide in the body, and then combined with riboadenin to form nicotinamide adenine dinucleotide (coenzyme I) and nicotinamide adenine dinucleotide phosphate (coenzyme II), which are necessary for lipid amino acid, protein, purine metabolism, tissue respiration oxidation and glycogenolysis. Nicotinic acid can reduce the utilization of coenzyme A; by inhibiting the synthesis of very low density lipoprotein (VLDL), it affects the transport of cholesterol in the blood. Large doses can reduce serum cholesterol and triglyceride concentrations. Nicotinic acid has a peripheral vasodilation effect. More |
59-67-6 | 15 |
Appearance
This product is in the form of tablets.
Indication
It is used to prevent and treat niacin deficiency diseases such as pellagra. It is also used as a vasodilator to treat hyperlipidemia. 2. Patients who strictly control or select their diet, or who receive parenteral nutrition, who have lost weight suddenly due to malnutrition, those who are pregnant or breastfeeding, those who take isoniazid, those who are severely addicted to tobacco, alcohol, or drugs, all have increased niacin requirements.
Usage and Dosage
Oral: 1. Adults: (1) Pellagra, usual dosage: 50-100 mg each time, 500 mg per day. If there is stomach discomfort, it is advisable to take it with milk or during meals. Generally, 5 mg each of vitamin B1, B2, and B6 are taken at the same time. (2) Anti-hyperlipidemia, start with 100 mg orally, 3 times a day, and increase to 1-2 g each time, 3 times a day after 4-7 days. 2. Children: Pellagra, usual dosage: 25-50 mg each time, 2-3 times a day.
Adverse Reactions
1. Niacin will hardly cause toxic reactions when kidney function is normal. 2. Common reactions of niacin include: feeling warm, redness of the skin, especially on the face and neck, and headache. 3. Large amounts of niacin can cause diarrhea, dizziness, fatigue, dry skin, itching, dry eyes, nausea, vomiting, stomach pain, etc. 4. Occasionally, large amounts of niacin can cause hyperglycemia, hyperuricemia, arrhythmia, and hepatotoxic reactions. 5. Generally, after taking niacin for 2 weeks, vasodilation and gastrointestinal discomfort can gradually adapt, and gradually increasing the dosage can avoid the above reactions. If there is severe skin flushing, itching, and gastrointestinal discomfort, the dosage should be reduced.
Precautions
(1) Those who are allergic to this drug. (2) Those with active peptic ulcer or arterial bleeding. (3) Those with unexplained elevated aminotransferase or active liver disease.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
Isoniazid can prevent niacin from binding to coenzyme I and cause niacin deficiency, so it is advisable to supplement niacin or niacinamide in appropriate amounts when taking isoniazid. 2. Niacin and vasodilators (such as guanethidine and other antihypertensive drugs) should not be used together. 3. If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Storage
Keep sealed.
Packaging Specification
0.1g
Validity Period
24 months
Manufacturer
Gansu Lanyao Pharmaceutical Co., Ltd.
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Founded in:
2006-12-22 -
Address:
No. 1739, Middle Section of Kunlunshan Avenue, Lanzhou New District, Lanzhou City, Gansu Province -
Tax NO.:
916200007948829218 -
Registered Funds:
84.5 million yuan -
Email: