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Diammonium Glycyrrhizinate Injection

Function and Efficacy

This product is an extract of the effective ingredients of Chinese medicinal liquorice, which has certain anti-inflammatory, liver cell membrane protection and liver function improvement effects. Pharmacological experiments have shown that oral administration of mice can reduce the increase of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) caused by carbon tetrachloride, thioacetamide and D-aminogalactic acid. It can also reduce the damage of D-aminogalactic acid to the liver and improve the chronic damage of the liver to the immune factors.

Ingredients

The main ingredient of this product is diammonium glycyrrhizinate. The excipients are water for injection and sodium hydroxide. Chemical name: 20β-carboxyl-11-oxo-n-oleanol-12-ene-3β-yl-2-O-β-D-glucopyranosiduronic acid-α-D-glucopyranosiduronic acid diammonium salt.

Name Description Content CAS NO. Manufacturer
Diammonium glycyrrhizinateIngredients

It has certain anti-inflammatory, liver cell membrane protection and liver function improvement effects. It can reduce the increase of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) caused by carbon tetrachloride, thioacetamide and D-aminogalactic acid, reduce the damage of D-aminogalactic acid to the liver and improve the chronic damage of immune factors to the liver.

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79165-06-3 35

Appearance

This product is a colorless clear liquid.

Indication

This product is suitable for acute and chronic viral hepatitis accompanied by elevated alanine aminotransferase (ALT).

Usage and Dosage

Intravenous drip, 150 mg at a time (3 vials at a time), diluted with 250 ml of 10% glucose injection and slowly dripped, once a day.

Adverse Reactions

1. Digestive system: poor appetite, nausea, vomiting, and abdominal distension may occur. 2. Cardiovascular system: common headaches, dizziness, chest tightness, palpitations, and increased blood pressure. 3. Others: itchy skin, urticaria, dry mouth, and edema. The above symptoms are generally mild and do not affect treatment.

Precautions

It is contraindicated in patients with severe hypokalemia, hypernatremia, hypertension, heart failure, and renal failure.

Special Population Medication

Precautions for children: The dosage and adverse reactions for newborns and infants have not been established yet, so it is not used for the time being. Precautions for pregnancy and lactation: Pregnant women should not use it. Precautions for the elderly:

Drug Interactions

When used in combination with diuretics such as uric acid, furosemide, ethiazide, trichloromethiazide, etc., the diuretic effect can enhance the potassium excretion effect of diammonium glycyrrhizinate contained in this product, which can easily lead to a decrease in serum potassium values. Special attention should be paid to the determination of serum potassium values.

Storage

Keep away from light and store in a sealed container.

Packaging Specification

10ml:50mg

Manufacturer

Jiangsu Langou Pharmaceutical Co., Ltd.

  • Founded in:

    2013-06-21
  • Address:

    No. 1, Langou Road, Xuzhou Industrial Park, Jiangsu
  • Tax NO.:

    91320305071075704T
  • Registered Funds:

    100 million yuan
  • Email:

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