Cinnarizine Tablets

This product is a piperazine calcium channel antagonist, which can block calcium influx into vascular smooth muscle, causing vasodilation and improving cerebral and coronary circulation, especially having a certain selective effect on cerebral blood vessels. This product can inhibit phosphodiesterase, prevent cAMP from decomposing into inactive 5-AMP, thereby increasing the concentration of cAMP in cells, inhibiting the release of various biologically active substances such as histamine, 5-hydroxytryptamine, bradykinin, and also inhibiting the activation of complement C4. The lethal dose for humans is 100-500 mg/kg, and the LD50 (oral administration to mice and rats) is greater than 1g/kg.

The main ingredients and chemical names of this product are: 1-diphenylmethyl-4-(3-phenyl-ethyl-propylene)-piperazine

This product is in the form of tablets.

It is used to treat cerebral thrombosis, cerebral embolism, cerebral arteriosclerosis, cerebral hemorrhage recovery period, subarachnoid hemorrhage recovery period, sequelae of brain trauma, inner ear vertigo, coronary artery sclerosis and diseases caused by poor peripheral circulation. In recent years, relevant literature reports show that this product can be used for allergic skin diseases such as chronic urticaria and senile skin itching.

Oral administration, 25-50 mg each time, 3 times a day.

Common symptoms include drowsiness, fatigue, and weight gain in some patients (generally transient). Long-term use may occasionally cause depression and extrapyramidal reactions, such as bradykinesia, rigidity, akathisia, dry mouth, muscle pain, and rash.

Patients with a history of allergy to this drug or a history of depression are contraindicated using this drug.

Precautions for children: Since this drug can pass through the blood-brain barrier, it has clear adverse reactions in the central nervous system and the central nervous system of children is sensitive to the drug; the metabolic function is relatively weak. Although there is no detailed research data on the use of drugs in children, in principle, children should be cautious or avoid using this drug. Precautions for pregnancy and lactation: Since this preparation is secreted with breast milk, although there are no research reports on teratogenicity and effects on embryonic development, in principle, pregnant women and lactating women should not use this drug. Precautions for the elderly: Since the nervous system of elderly patients is more sensitive, the dosage should be reduced.

(1) When used in combination with alcohol, hypnotics or sedatives, the sedative effect is aggravated. (2) When used in combination with phenytoin sodium or carbamazepine, the blood concentration of cinnarizine can be reduced.

Shade, sealed and stored

25mg

36 months

Furen Pharmaceutical Group Co., Ltd.

• Founded in:

  1997-01-22

• Address:

  No. 1 Tongyuan Road, Luyi County Industrial Cluster Area

• Tax NO.:

  9141000017569469XJ

• Registered Funds:

  400 million yuan

• Email:

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