Compound Lophatherum gracile tablets

This product was administered orally to experimental dogs with renal hypertension at a dose of 0.2g/kg, which significantly reduced blood pressure from 190/142 to 153/98mmHg 2 hours after oral administration. This product was administered orally to dogs and cats at 0.2 and 0.4g/kg, which slowed the heart rate 20 minutes later and lasted for 5 hours. This product was administered orally to rats at 0.3 and 0.6g/kg, which significantly counteracted arrhythmias caused by aconitine, calcium chloride and coronary artery ligation, and its anti-arrhythmic mechanism may be related to the effect on calcium ion influx. This product was administered orally to mice at 0.6 and 1.2g/kg, which reduced spontaneous activity in mice, and had a synergistic effect with sodium pentobarbital, causing the mice to lose their righting reflex.

Apocynum venetum, wild chrysanthemum, tetrandrachidia tertium, guanidine sulfate, hydralazine, chlordiazepoxide, and vitamin B1.

This product is a sugar-coated tablet.

Used for hypertension.

Oral, usual dosage: three times a day, two tablets each time. Maintenance dosage: two tablets a day after blood pressure drops

Oral administration of Lophatherum preparations often causes bowel sounds, diarrhea, occasional stomach pain, dry mouth and other adverse reactions, and some patients experience asthma and liver pain; cardiotoxicity is mainly bradycardia and premature contractions. Excessive use can cause sedation, drowsiness, fatigue, etc., and can also cause an increase in blood uric acid.

It is contraindicated for those who are allergic to this product.

Precautions for children: Reduce the dosage or follow the doctor's advice. Precautions for pregnancy and lactation: This product is not the first choice for pregnant and lactating women with hypertension. Precautions for the elderly: Not yet clear.

-Atropine: can partially counteract the antihypertensive effect of Apocynum venetum leaves. -Diphenhydramine: can block the antihypertensive effect of Apocynum venetum leaves by more than 50%. Other antihypertensive drugs: Apocynum venetum can be used in combination with external Chinese medicine patches such as Li's Medicinal Patch, Jiangya Shen Patch, and Xuanya Patch to enhance the antihypertensive effect. For other drug interactions, please consult your doctor or pharmacist.

Keep tightly closed.

Compound

24 months

Huangshan Tianmu PHARMA Co., Ltd.

• Founded in:

  1997-10-28

• Address:

  No. 7, Hanlin Road, Huangshan Economic Development Zone, Huangshan City, Anhui Province

• Tax NO.:

  91341000151488891C

• Registered Funds:

  30 million yuan

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