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Amantadine Hydrochloride Tablets

Function and Efficacy

This product was originally an antiviral drug. Its anti-Parkinson's disease mechanism is mainly to promote the synthesis and release of striatal dopamine, reduce the reuptake of dopamine by nerve cells, and have an anti-acetylcholine effect, thereby improving the symptoms of Parkinson's patients.

Ingredients

The main ingredient of this product is adamantane hydrochloride, and its chemical name is: tricyclo[3,3,1,13,7]decane-1-amine hydrochloride. Its structural formula is: C10H17NHCl187.71

Name Description Content CAS NO. Manufacturer
1-Adamantanamine hydrochlorideIngredients

It promotes the synthesis and release of dopamine in the striatum, reduces the reuptake of dopamine by nerve cells, and has an anti-acetylcholine effect, thereby improving the symptoms of Parkinson's disease patients.

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665-66-7 13

Appearance

This product is white tablets.

Indication

It is used for Parkinson's disease, Parkinson's syndrome, drug-induced extrapyramidal disorders, Parkinson's syndrome after carbon monoxide poisoning, and Parkinson's syndrome in the elderly with cerebral arteriosclerosis. It is also used to prevent and treat respiratory infections caused by influenza A virus.

Usage and Dosage

For Parkinson's disease and Parkinson's syndrome, take 100 mg orally, 1 to 2 times a day, and the maximum daily dose is 400 mg. For antiviral treatment, adults take 200 mg once a day or 100 mg once every 12 hours; children aged 1 to 9 years old take 1.5 to 3 mg/kg according to body weight once every 8 hours, or 2.2 to 4.4 mg/kg once every 12 hours; children aged 9 to 12 years old take 100 mg orally every 12 hours; children aged 12 years and above take the same dosage as adults.

Adverse Reactions

Dizziness, insomnia and nervousness, nausea, vomiting, anorexia, dry mouth, constipation. Occasionally, depression, anxiety, hallucinations, mental confusion, ataxia, headache, and rarely, convulsions. Rarely, leukopenia and neutropenia.

Precautions

People who are allergic to this product.

Special Population Medication

Precautions for children: It is forbidden to use in newborns and infants under 1 year old. Precautions for pregnancy and lactation: 1. This product can pass through the placenta. Animal experiments have found that when rats are used 50mg/kg daily (12 times the usual dose for humans), it is toxic to the embryo and can cause teratogenesis. Pregnant women should use it with caution. 2. This product can be excreted in breast milk and is forbidden to use in lactating women. Precautions for the elderly: Use with caution.

Drug Interactions

1. This product combined with ethanol can enhance the central inhibition effect. 2. This product combined with other anti-Parkinson's disease drugs, anticholinergic drugs, antihistamines, phenothiazines or tricyclic antidepressants can enhance the anticholinergic reaction. 3. This product combined with central nervous system stimulants can enhance the excitement of the central nervous system, and in severe cases can cause convulsions or arrhythmias.

Storage

Keep away from light and store in sealed container.

Packaging Specification

0.1g

Validity Period

36 months

Manufacturer

Jia Mu Si Luling Sunflower Pharmaceutical Group Co., Ltd.

  • Founded in:

    1999-12-14
  • Address:

    No. 91, Wusulijiang Street, Dongfeng District, Jiamusi City, Heilongjiang Province
  • Tax NO.:

    91230800716614462L
  • Registered Funds:

    21.264 million yuan
  • Email:

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