Fenbufen Tablets

1This product is a long-acting non-steroidal anti-inflammatory drug. It can inhibit the activity of cyclooxygenase and reduce the synthesis of prostaglandins. 2Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. 3Acute toxicity test results: The oral LD50 of rats is 200-720mg/kg, and the intraperitoneal injection LD50 is 265-575mg/kg; the oral LD50 of mice is 795-1673mg/kg, and the intraperitoneal injection LD50 is 506-811mg/kg.

The main ingredient of this product is fenbufen (C16H14O3), whose chemical name is 3-(4-biphenylcarbonyl) propionic acid. Its structural formula is: Molecular formula: C16H14O3 Molecular weight: 254.28

This product is white or off-white tablets.

It is mainly used for rheumatoid arthritis, rheumatic arthritis, osteoarthritis, gout, ankylosing spondylitis, etc., and can also be used for other painful diseases.

Oral administration: Adults: 0.3g each time, twice a day (three times if necessary) or as directed by a doctor.

The adverse reactions of this product are mainly gastrointestinal reactions, manifested as stomach pain, burning sensation, nausea, and a few serious adverse reactions include gastric ulcer, bleeding, and even perforation. Dizziness, rash, mild decrease in white blood cell count, mild increase in serum transferase, etc. are less common.

1. Patients who are allergic to this product are prohibited from using it. 2. Patients with peptic ulcer, severe liver and kidney damage, and aspirin-induced asthma are prohibited from using it.

Precautions for children: follow the doctor's advice. Precautions for pregnancy and lactation: follow the doctor's advice. Precautions for the elderly: This product is a long-acting non-steroidal anti-inflammatory drug. It can inhibit the activity of cyclooxygenase and reduce the synthesis of prostaglandins to work. Animal experiments show that the anti-inflammatory and analgesic effects of this product are weaker than indomethacin, but stronger than aspirin. Results of acute toxicity tests: The oral LD50 of rats is 200-720 mg/kg, and the intraperitoneal injection LD50 is 265-575 mg/kg; the oral LD50 of mice is 795-1673 mg/kg, and the intraperitoneal injection LD50 is 506-811 mg/kg.

There may be cross-allergic reactions with other nonsteroidal anti-inflammatory drugs.

Keep away from light, sealed and stored in a dry place.

0.3g

24 months

Jiangxi Health Pharmaceutical Co., Ltd.

• Founded in:

  1999-05-04

• Address:

  Yichun Yuanzhou Pharmaceutical Industrial Park

• Tax NO.:

  913609001609615995

• Registered Funds:

  91.25 million yuan

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