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Gentamycin Sulfate Tablets

Function and Efficacy

This product is an aminoglycoside antibiotic. It has good antibacterial effects on various Gram-negative and Gram-positive bacteria, and has good antibacterial effects on various Enterobacteriaceae such as Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Enterobacter, Serratia and Pseudomonas aeruginosa. Neisseria and Haemophilus influenzae are moderately sensitive to this product. It also has certain effects on Brucella, Yersinia pestis, Acinetobacter and Campylobacter fetus. It has good antibacterial effects on about 80% of methicillin-sensitive strains of Staphylococcus (including Staphylococcus aureus and coagulase-negative Staphylococcus), but methicillin-resistant strains are mostly resistant to this product. It has poor effects on Streptococcus and Streptococcus pneumoniae, and Enterococcus is mostly resistant to this product. When this product is used in combination with β-lactams, most of them can obtain synergistic antibacterial effects. The mechanism of action of this product is to bind to the 30S subunit of the bacterial ribosome and inhibit the synthesis of bacterial proteins. In recent years, the number of Gram-negative bacteria resistant to gentamicin has increased significantly.

Ingredients

The main ingredient of this product is gentamicin sulfate, which is a multi-component antibiotic containing components such as C1, C1a, C2a, and C2.

Name Description Content CAS NO. Manufacturer
Gentamicin sulfateIngredients

Aminoglycoside antibiotics have good antibacterial effects on Gram-negative and Gram-positive bacteria, and inhibit bacterial protein synthesis by binding to the bacterial ribosome 30S subunit.

More
1405-41-0 29

Appearance

This product is a white tablet or sugar-coated tablet, which appears white or off-white after removing the coating.

Indication

This product is suitable for the treatment of bacterial dysentery or other bacterial intestinal infections, and can also be used for preoperative preparation for colon surgery.

Usage and Dosage

Oral administration: Adults: 240-640 mg per day, divided into 4 doses; children: 5-10 mg/kg per day, divided into 4 doses.

Adverse Reactions

A small number of patients may experience loss of appetite, nausea, diarrhea, etc. after taking the medicine.

Precautions

Patients who are allergic to this product or other aminoglycoside antibiotics are contraindicated.

Drug Interactions

1. When used in combination with other aminoglycosides or used in sequence, it may increase the possibility of ototoxicity, nephrotoxicity and neuromuscular blocking effects. When used in combination with neuromuscular blockers, it may aggravate neuromuscular blocking effects. 2. When used in combination with capreomycin, cisplatin, ethacrynic acid, furosemide or vancomycin or used in sequence, it may increase the possibility of ototoxicity and nephrotoxicity. 3. When used in combination with cephalothin, it may increase nephrotoxicity. 4. When used in combination with polymyxins or used in sequence, it may increase nephrotoxicity and neuromuscular blocking effects. 5. Other nephrotoxic and ototoxic drugs should not be used in combination with this product or used in sequence to avoid aggravating nephrotoxicity or ototoxicity.

Storage

Sealed, store in a cool, dark and dry place.

Packaging Specification

40mg (40,000 units)

Manufacturer

Fujian Gutian Pharmaceutical Co., Ltd.

  • Founded in:

    1997-08-12
  • Address:

    No. 1, Song'an Branch Road, Chengxi Street, Gutian County, Fujian Province
  • Tax NO.:

    91350922157620646F
  • Registered Funds:

    180 million yuan
  • Website:

  • Email:

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