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Chloramphenicol eye drops

Function and Efficacy

This product is a chloramphenicol antibiotic. It has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. It only has antibacterial effects on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are usually resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus. This product is an antibacterial agent. Chloramphenicol is fat-soluble and enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of the bacterial ribosome, which blocks the growth of the peptide chain (possibly due to the inhibition of the action of transpeptidase), thereby inhibiting the formation of the peptide chain and preventing protein synthesis.

Ingredients

The main component of this product is chloramphenicol, and its chemical name is D-threo-(-)-N-[alpha;-(hydroxymethyl)-beta;-hydroxy-p-nitrophenylethyl]-2,2-dichloroacetamide. Its structural formula is: Molecular formula: C11H12Cl2N2O5 Molecular weight: 323.13

Name Description Content CAS NO. Manufacturer
ChloramphenicolIngredients

This product is a chloramphenicol antibiotic. It has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative and Gram-positive bacteria, anaerobes, Rickettsia, spirochetes and Chlamydia. It has bactericidal effects on the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis. It only has antibacterial effects on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic Streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Salmonella typhi, Salmonella paratyphi, Shigella, Bacteroides fragilis and other anaerobic bacteria. The following bacteria are usually resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, indole-positive Proteus, methicillin-resistant Staphylococcus and Enterococcus. This product is an antibacterial agent. Chloramphenicol is fat-soluble and enters bacterial cells by diffusion, and reversibly binds to the 50S subunit of the bacterial ribosome, which blocks the growth of the peptide chain (possibly due to the inhibition of the action of transpeptidase), thereby inhibiting the formation of the peptide chain and preventing protein synthesis.

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Appearance

This product is a colorless or almost colorless clear liquid.

Indication

Used to treat eye infections caused by Escherichia coli, Haemophilus influenzae, Klebsiella, Staphylococcus aureus, hemolytic Streptococcus and other sensitive bacteria, such as trachoma, conjunctivitis, keratitis, blepharitis, etc.

Usage and Dosage

Apply inside the eyelids, 1 to 2 drops at a time, 3 to 5 times a day.

Adverse Reactions

May cause eye irritation, allergic reaction, etc.

Precautions

It is contraindicated for those who are allergic to this product.

Special Population Medication

Precautions for children: It is forbidden to use in newborns and premature infants. Precautions for pregnancy and lactation: Although this product is a local medication, chloramphenicol has a serious bone marrow suppression effect. It may cause serious adverse reactions in newborns and breastfeeding infants after use by pregnant and lactating women. Therefore, pregnant and lactating women should use it with caution. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

Drug Interactions

Combination use with macrolide antibiotics such as lincomycin or erythromycin may cause antagonism, so it is not suitable for combined use.

Storage

Keep away from light, tightly closed and in a cool place.

Packaging Specification

8 ml: 20 mg

Validity Period

12 months.

Manufacturer

Xinxiang Huaqing Pharmaceuticals Co., Ltd.

  • Founded in:

    2005-12-19
  • Address:

    South of Bridge No. 21, Xinzheng Highway, Xinxiang City
  • Tax NO.:

    91410700783402195G
  • Registered Funds:

    50 million yuan
  • Website:

  • Email:

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